Specimens containing Rheumatoid factor (RF) were examined for possible interference in Prolactin (PRL) measurement. PRL levels following polyethylene glycol (PEG) treatment were significantly lower than in untreated RFpositive samples (p<0.001; n=43) and spurious hyperprolactinemia was indicated in 7 percent. Gel filtration chromatography suggested that the PRL-like immunoreactivity was from as...

All patients with pituitary incidentaloma should be investigated for pituitary hyperfunction. The single most important test is measurement of serum prolactin (PRL). Elevated PRL can indicate either direct tumour secretion (levels are typically 800–2,000 mU/l for microprolactinoma, >2,000 mU/l for macroprolactinoma and <600 normally) or ‘disconnection’ of the hypothalamus and normal pituitary g...

Introduction: Macroprolactin may interfere with hormonal assay and falsely increase serum prolactin levels. Therefore, failure to identify macroprolactinemia can lead inappropriate investigations treatment in women already susceptible anxiety stress. The aim of this study was among childbearing age hyperprolactinemia.Materials methods: A cross-sectional conducted a tertiary care setting at the ...

was performed in 150 mL of a 1 g/L silver nitrate solution for 10 min at room temperature with gentle shaking. The gel was rinsed twice with distilled water to remove excess silver solution and was developed in a solution containing, per liter, 15g of NaOH, 0.1 g of NaBH4, and 0.48 g of formaldehyde. The gel was first washed in 150 mL of this solution (for ;30 s) to precipitate the excess silve...