نتایج جستجو برای: m2 gene

تعداد نتایج: 1181315  

2014
Junping Ren Guangliang Liu Jonathan Go Deepthi Kolli Guanping Zhang Xiaoyong Bao

Human metapneumovirus (hMPV) is a leading cause of lower respiratory infection in young children, the elderly and immunocompromised patients. Repeated hMPV infections occur throughout life. However, immune evasion mechanisms of hMPV infection are largely unknown. Recently, our group has demonstrated that hMPV M2-2 protein, an important virulence factor, contributes to immune evasion in airway e...

Journal: :Cancer research 2006
Jun Yin Ayako Hashimoto Mineko Izawa Keiko Miyazaki Guo-Yun Chen Hiromu Takematsu Yasunori Kozutsumi Akemi Suzuki Kimio Furuhata Feng-Leng Cheng Chun-Hung Lin Chihiro Sato Ken Kitajima Reiji Kannagi

Tumor hypoxia figures heavily in malignant progression by altering the intracellular glucose metabolism and inducing angiogenic factor production, thus, selecting and expanding more aggressive cancer cell clones. Little is known, however, regarding hypoxia-induced antigenic changes in cancers. We investigated the expression of N-glycolyl sialic acid (NeuGc)-G(M2), a cancer-associated gangliosid...

Journal: :The Journal of general virology 2004
J Pedro Simas Sofia Marques Anne Bridgeman Stacey Efstathiou Heiko Adler

Infection of mice with murine gammaherpesvirus 68 is characterized by a marked transient expansion of latently infected splenic germinal centre (GC) B cells, which is followed by lower levels of persistent infection in GC and memory B cells. Virus transcription within GC B cells is restricted to a number of latency-associated open reading frames, including M2. This gene encodes a structurally u...

Journal: :reports of biochemistry and molecular biology 0
saeedeh ghazaey zidanloo department of molecular and cell biology, faculty of basic sciences, university of mazandaran, babolsar, cp: 47416-95447, iran abasalt hosseinzaeh colagar tel: +98 1125342452; fax: +98 1125342452

background: the human aml1 gene, located on chromosome 21, can be fused to the aml1- eight-twenty-one (eto) oncoprotein on chromosome eight, resulting in a t(8;21)(q22;q22) translocation. acute myeloid leukemia (aml) associated with this translocation is considered a distinct aml with a favorable prognosis. due to the various incidences of the translocation, which is associated with geographic ...

Journal: :Molecular human reproduction 2012
G Tiscia D Colaizzo G Favuzzi P Vergura P Martinelli M Margaglione E Grandone

Hereditary thrombophilias can impair vascular placental functions and predispose to the birth of small-for-gestational age (SGA) babies. The placental anticoagulant protein annexin A5 (ANXA5) may contribute to this process. A functional haplotype (M2) within the ANXA5 gene is associated with fetal loss and venous thrombosis. This study investigated the prevalence of the M2 haplotype in a group ...

Journal: :archives of razi institute 2016
s. moradi bidhendi h. toghyani h.r. varshovi h. paykari a. mirjalili

the present study was aimed to construct a fusion plasmid harboring the extracellular domain of the influenza a m2-protein (m2e), which was fused to the n-terminus of the truncated hsp70 (hsp70359–610) molecule as a new approach for future vaccine research against influenza a. the amplified fragments, m2e and hsp70359-610 genes, were gel-purified. the products were then single digested with bam...

Journal: :Proceedings of the National Academy of Sciences 1982

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