In order to assess the relevance of canine splenic pathology, to emphasise the differential diagnostic criteria among splenic haematoma, haemangioma and haemangiosarcoma, and to focus on the recently proposed classification of canine splenic fibrohistiocytic nodules (FHN), a retrospective study was carried out on HE-stained sections from formalin-fixed and paraffin-embedded samples from 109 spl...

Purpose. Secondary hyperparathyroidism with nodular hyperplasia is resistant to medical therapies. Cinacalcet is an effective treatment for severe secondary hyperparathyroidism. This multicentre retrospective study was designed to determine the long-term efficacy of cinacalcet in patients with nodular hyperplasia, the advanced type of parathyroid hyperplasia. Subjects and methods. The study sub...

A 4-year-old boy is sent to paediatric consultation for nightrecurring abdominal pain of 3 weeks duration. Clinical examination reveals a moderate pain to deep palpation of the right iliac fossa. The rest of the clinical examination is unremarkable. Ultrasound (US) shows a slightly swollen 7 mm transverse diameter appendix, electively sensitive. Swelling is the result of hypoechogenic submucosa...

1. Richardson PG, Elias AD, Krishnan A, et al.Treatment of severe veno occlusive disease with defribotide: compassionate use results in efficacy without significant toxicity in high risk population. Blood 1997; 90(Suppl 1):252a. 2. Thung SN, Gerber MA, Bodenheimer HC Jr. Nodular regenerative hyperplasia of the liver in a patient with diabetes mellitus. Cancer 1982; 49:543-6. 3. Duvoux C, Kracht...

BACKGROUND Lymphoid aggregates are normally found throughout the small and large intestine. Known as lymphoid nodular hyperplasia (LNH), these aggregates are observed especially in young children and are not associated with clinical symptoms being considered 'physiological'. In children presenting with gastrointestinal symptoms the number and size of the lymphoid follicles are increased. Patien...

Reactive lymphoid hyperplasia (RLH) of the liver is a rare entity and has also been termed nodular lymphoid lesion or pseudolymphoma of the liver. We report a case of hepatic RLH exhibiting unusual histiocyte-rich histologic features in a 47-yr-old woman in conjunction with a renal cell carcinoma. A follow-up computed tomography scan was done 14 months after a right radical nephrectomy for rena...