Circulating filarial antigen (Ag) prevalence, measured using rapid point-of-care tests, is the standard indicator used for monitoring and surveillance in Global Program to Eliminate Lymphatic Filariasis. In 2015, immunochromatographic test (ICT) was replaced with filariasis strip (FTS), which has higher reported sensitivity. Despite differences sensitivity, no changes recommended targets were m...

Brugian filariasis prevalent mostly in South-East Asian countries including India contributes to a small but significant proportion of the socioeconomic burden due to lymphatic filariasis. Along with bancroftian filariasis, brugian filariasis has been targeted for elimination globally. The lack of a reliable daytime diagnostic test has been seen as an important barrier to the successful impleme...

Entomological and epidemiological data of Lymphatic Filariasis (LF) was collected from 120 villages of four districts of Andhra Pradesh, India. Self-Organising Maps (SOMs), data-mining techniques, was used to classify and prioritise the endemic zones of filariasis. The results show that, SOMs classified all the villages into three major clusters by considering the data of Microfilaria (MF) rate...

The newly-introduced Brugia Rapid dipstick for filarial antibodies and ICT filarial antigen card test were used to confirm historical data on the distribution of lymphatic filariasis in the Republic of Timor-Leste. Twelve out of thirteen districts were confirmed as being endemic. Brugian filariasis predominates, with an average prevalence of 11.6%. The average prevalence of Bancroftian filarias...

BACKGROUND Papua New Guinea is the only endemic country in the Western Pacific Region that has not yet introduced a countrywide programme to eliminate lymphatic filariasis. However, on Misima Island in Milne Bay Province, government and private sectors have collaborated to implement a pilot elimination programme. Although interim evaluation indicated that the programme has been parasitologicall...

It is estimated that every year at least 500 million people in the world suffer from one or the other tropical diseases that include malaria, lymphatic filariasis, schistosomiasis, dengue, trypanosomiasis and leishmaniasis. Of late chikungunya, a serious mosquito borne epidemic has gained momentum in India. One to two million deaths are reported annually due to malaria worldwide. Lymphatic fila...

Over 892 million people in 48 countries are at risk of infection by nematodes that cause lymphatic filariasis. As part the Global Programme to Eliminate Lymphatic Filariasis, mass drug administration is distributed communities until surveillance indicates rates below target prevalence thresholds. In some countries, including American Samoa, filariasis transmission persists despite years and/or ...

In 1997, the World Health Assembly resolved that human infection with the lymphatic filarial parasite Wuchereria bancrofti—a nematode parasite transmitted by mosquitoes, which causes elephantiasis, disfigurement of the male genitalia, and acute adenolymphangitis in tropical and subtropical Africa, South Asia, the Pacific, and Latin America—could be eradicated using available public health inter...

In view of the recent discovery of rickettsial endosymbionts, Wolbachia in lymphatic filarial parasites, Wuchereria bancrofti and Brugia malayi and subsequently of their vital role in the survival and development of the latter, antibiotics such as tetracycline are being suggested for the treatment of lymphatic filariasis, by way of eliminating the endosymbiont. But, it is essential to assess th...