BACKGROUND To investigate the impact of left ventricular (LV) diastolic functional recovery on major adverse cardiac events (MACE) 6 months after acute myocardial infarction (AMI) in patients with preserved LV systolic function. METHODS A total 463 patients with preserved LV systolic function at 6 months after an AMI were divided into two groups based on the extent of diastolic recovery asses...

OBJECTIVES We tested the feasibility of using analysis of color kinesis images to objectively assess global and regional left ventricular (LV) diastolic function in patients with dilated cardiomyopathy (DCM). In addition, the ability of this technique to track drug-induced changes on LV diastolic properties was studied. BACKGROUND Diastolic dysfunction contributes to symptomatology in patient...

conclusions silent ventricular systolic dysfunction was more common in the patients with sle than in the control group. newer echocardiographic techniques such as two-dimensional ste provide an earlier chance for the detection of subclinical lv systolic dysfunction. our findings were independent of the traditional risk factors. results the mean duration of sle was 5.5 ± 3.4 years in our patient...

BACKGROUND Previous experimental studies have shown that nitric oxide (NO) modulates cardiac function by an abbreviation of systolic contraction and an enhancement of diastolic relaxation. However, the response to NO donors of patients with severe pressure-overload hypertrophy and diastolic dysfunction is unknown. METHODS AND RESULTS Intracoronary NO donors were given to 17 patients with seve...

AIMS To evaluate the relationships between measures of left ventricular (LV) filling dynamics at cadmium-zinc-telluride (CZT) imaging and indexes of LV diastolic function at transthoracic echocardiography. METHODS AND RESULTS Two hundred and forty-seven patients underwent myocardial perfusion imaging at rest and after stress with a low-dose CZT protocol and a baseline transthoracic echocardio...

introduction: we aimed to assess whether the vasodilator effect of oral dipyridamole on the left ventricular systolic function in patients with suspected cad is different from that of intravenous (iv) dipyridamole using tc-99m mibi myocardial perfusion gated spect. methods: eighty-nine patients (17 m / 72 w; 61 ± 10 years) were enrolled in this study. the patients underwent a dipyridamole stres...

The term “diastology” characterises left ventricular (LV) relaxation, filling dynamics and their integration into clinical practice. Recent advances in echocardiography have enabled the understanding of this complex process, particularly relevant in the setting of an aging population and rising prevalence of heart failure (HF) with preserved systolic function. Data from the Mayo Clinic and othe...

BACKGROUND There has been an increasing interest in use of mineralocorticoid receptor antagonists (MRAs) in patients with heart failure with preserved ejection fraction (HFPEF). However, a comprehensive evaluation of MRA effects on left ventricular (LV) structure and function in these patients is lacking. In this meta-analysis, we evaluated the effects of MRAs on LV structure and function among...

BACKGROUND We undertook a cross-sectional study to test the hypothesis that patients with hypertrophic cardiomyopathy (HCM) who have impaired left ventricular (LV) diastolic function are insulin resistant. We also evaluated the relation between the development of atrial fibrillation (AF) and insulin resistance (IR) in patients with HCM. METHODS AND RESULTS Eighty-eight patients with HCM (71 m...

BACKGROUND Subclinical left ventricular (LV) diastolic dysfunction in type 2 diabetes (T2D) is a common finding and represents an early sign of diabetic cardiomyopathy. However, the relationship between LV diastolic dysfunction and the incident T2D has not been previously studied. METHODS A total of 1817 non-diabetic participants (mean age, 54 years; 48% men) from the Korean Genome and Epidem...