نتایج جستجو برای: lowdensity lipoprotein ldl

تعداد نتایج: 66227  

Journal: :galen medical journal 0
karoon shahebrahimi assistant professor of endocrinology and metabolism kermanshah university of medical sciences, kermanshah, bagh abrisham, imam reza hospital rozita naseri kermanshah university of medical sciences, iran tahereh sadat kalantarian imam reza hospital, kermanshah university of medical sciences, kermanshah, iran mehrali rahimi kermanshah university of medical sciences, iran farid najafi kermanshah university of medical sciences, iran katayoun derakhshandeh school of pharmacy, kermanshah university of medical sciences, kermanshah, iran

background: studies demonstrated controversial results on subclinical hypothyroidism (sch) regarding lipid profile alteration with or without levothyroxine treatment. the purpose of this study is to investigate the effects of levothyroxine on serum lipids in sch. materials and methods: one hundred patients with sch referred to taleghani hospital in kermanshah were recruited and randomly assigne...

Journal: :iranian biomedical journal 0
محمدعلی غفاری mohammad ali ghaffari صمد مجاب samad mojab

background: it is well established that oxidative modification of low density lipoprotein (ldl) plays a causal role in human atherogenesis and the risk of atherosclerosis is increased in patients with diabetes mellitus. we examined the in vitro effect of glucose on native and glycated ldl oxidation using copper ion dependent oxidation system. methods: in this study, ldl was isolated from plasma...

Journal: :Medula: Jurnal Ilmiah Fakultas Kedokteran Universitas Halu Oleo 2022

Background: Premenopausal is a period that women will experience before heading to the menopause phase in age range of 4 5-55 years. In premenopausal it characterized by instability hormone estrogen which affect lipid metabolism closely related increase abdominal fat known as or central obesity . The results hormonal changes levels lipids body such TG and LDL-Chol blood. Purpose(s): This study ...

Journal: :The American journal of clinical nutrition 1995
R M Krauss D M Dreon

Lipid and lipoprotein responses to reduced dietary fat intake were investigated in relation to differences in distribution of low-density-lipoprotein (LDL) subclasses among 105 healthy men consuming high-fat (46% fat) and low-fat (24% fat) diets in random order for 6 wk each. With high-fat diets, 87 subjects had predominantly large, buoyant LDL (pattern A), whereas the remainder had primarily s...

2017
Kaustubh Bora Probodh Borah

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Requirement for Appropriate Methodology to Evaluate the Clinical Relevance of the Difference ...

Journal: :Annals of clinical biochemistry 2010
Toshihiro Sakurai Suchin Trirongjitmoah Yuka Nishibata Takeshi Namita Masahiro Tsuji Shu-Ping Hui Shigeki Jin Koichi Shimizu Hitoshi Chiba

BACKGROUND A simple method for the measurement of LDL particle sizes is needed in clinical laboratories because a predominance of small, dense LDL (sd LDL) has been associated with coronary heart disease. We applied dynamic light scattering (DLS) to measure lipoprotein particle sizes, with special reference to sd LDL. METHODS Human serum lipoproteins isolated by a combination of ultracentrifu...

Journal: :Circulation 2004
Rafael Carmena Patrick Duriez Jean-Charles Fruchart

The importance of low-density lipoprotein (LDL) cholesterol in the development of atherosclerosis has long been recognized, and LDL cholesterol remains the primary target of therapy for the prevention of coronary heart disease. Nevertheless, increasing research attention over the past decade has been devoted to the heterogeneity of LDL particles and the atherogenicity of lipids and lipoproteins...

2001
Michael Kapinsky Michael Torzewski Christa Büchler Chinh Quoc Duong Gregor Rothe Gerd Schmitz

Heterogeneity of peripheral blood monocytes is characterized by specific patterns in the membrane expression of Fc g-receptor III (FcgRIII/CD16) and the lipopolysaccharide receptor (LPS receptor CD14), allowing discrimination of distinct subpopulations. The aim was to analyze the correlation of these phenotypic differences to the early interaction of freshly isolated monocytes with modified lip...

Journal: :Arteriosclerosis 1984
H R Slater L McKinney C J Packard J Shepherd

Receptor-mediated catabolism of low density lipoprotein (LDL) by cultured cells depends on the presence of functionally significant arginine and lysine residues on the lipoprotein apoprotein. When these are blocked, the recognition process is abolished, and catabolism of the modified lipoprotein is restricted to other mechanisms. Accurate discrimination between the activities of the receptor an...

Journal: :Journal of the American College of Cardiology 2012
Emil M deGoma Daniel J Rader

Limitations in our ability to predict cardiovascular risk have fueled efforts to identify novel risk markers and to refine the measurement of traditional risk factors, such as low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C). Standard assays to evaluate LDL-C and HDL-C quantify the cholesterol content within the respective lipoprotein fraction. Howeve...

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