Recent trial results suggest that the consumption of a low glycemic index (GI) diet is beneficial in the prevention of high blood glucose levels. Identifying active hypoglycemic substances in ordinary foods could be a significant benefit to the management of blood glucose. It has been hypothesized that noodles with Bombyx mori powder are a low GI food. We evaluated GI and changes in postprandia...

Glycemic index (GI), a measure of blood glucose level as influenced by foods has become a concern due to the increasing cases of diabetes in Ghana. In spite of this, little is known of the GI of commonly consumed carbohydrate-rich foods of the Ghanaian diet. The GI of five Ghanaian staples: fufu (locally pounded), kenkey (Ga), banku, Tuo Zaafi (TZ), and fufu (Processed powder) were determined i...

This study assessed the effect of changes in glycemic index (GI) and load (GL) on weight loss and glycated hemoglobin (HbA1c) among individuals with type 2 diabetes beginning a vegan diet or diet following the 2003 American Diabetes Association (ADA) recommendations. The study was a 22-wk, randomized trial of 99 participants with type 2 diabetes who were counseled to follow 1 of 2 diet treatmen...

BACKGROUND Maternal diet is known to impact pregnancy outcome. Following a low glycemic index (GI) diet during pregnancy has been shown to improve maternal glycemia and reduce infant birthweight and may be associated with a higher fibre intake. We assessed the impact of a low GI dietary intervention on maternal GI, nutritional intake and gestational weight gain (GWG) during pregnancy. Complianc...

Fish oil rich in n-3 polyunsaturated fatty acids is known to attenuate diet-induced obesity and adipose tissue inflammation in rodents. Here we aimed to investigate whether different carbohydrate sources modulated the antiobesity effects of fish oil. By feeding C57BL/6J mice isocaloric high-fat diets enriched with fish oil for 6 wk, we show that increasing amounts of sucrose in the diets dose-d...

BACKGROUND The optimal combination of diet and exercise that produces the greatest reversal of obesity-related insulin resistance is unknown. OBJECTIVES We examined the effects of a combined 7-d low-glycemic index (low-GI) diet and exercise training intervention on insulin sensitivity in older obese humans. DESIGN Participants [n = 32; mean (+/-SEM) age: 66 +/- 1 y; body mass index (in kg/m...

Background: Adequate nutritional status is a critical determinant of the onset and maintenance of normal reproductive function. More than 50% of women with PCOS are obese and central obesity plays a central role in the pathogenesis of PCOS by generating an insulin- resistant state, It has been proposed that recurrent hypoglycaemia due to hyperinsulinaemia could lead to decreased post-prandial s...

Background: Polycystic ovary syndrome (PCOS) is the most common endocrine disease in women affecting 5-10% of those of childbearing age. The majority of women with PCOS, regardless of weight, have a form of insulin resistance that is intrinsic to the syndrome. Obese women with PCOS have an added burden of insulin resistance related to their adiposity. Given the association of obesity and insuli...

BACKGROUND Although the associations of dietary glycemic index (GI) and dietary glycemic load (GL) with many chronic diseases have been examined in epidemiologic studies, information regarding the reproducibility and validity of these measures assessed with the use of food-frequency questionnaires (FFQs) is lacking. OBJECTIVE We examined the reproducibility and validity of dietary GI and diet...

The glycemic index (GI) of ingested carbohydrates may influence substrate oxidation during exercise and athletic performance. Therefore, the aim of this study was to assess the effect of low- and moderate-GI three-week diets on aerobic capacity and endurance performance in runners. We conducted a randomized crossover feeding study of matched diets differing only in GI (low vs. moderate) in 21 e...