A gelatin phantom containing an optically scattering funnel-shaped region of elevated optical density (OD) was used to examine light-scattering-induced artefacts in a cone-beam optical CT scanner used for gel dosimetry. To simulate polymer gel dosimeters, the opacity was introduced by adding a colloidal scatterer to the gelatin. Scatter results in an underestimate of OD (hence dose). In line pr...

Background: Gold nanoparticles (GNPs) are among the most promising radiosensitive materials in radiotherapy. Studying the effective sensitizing factors such as nanoparticle size, concentration, surface features, radiation energy and cell type can help to optimize the effect and possible clinical application of GNPs in radiation therapy. In this study, the radiation sensitive polymer gel was use...

Introduction: The purpose of the current study was to investigate the effect of X-ray spectra on the sensitivity of a polymer gel dosimeter imaged with a conventional computed tomography (CT) scanner. Material and Methods: The whole process of CT imaging of an irradiated polymer gel was simulated by MCNPX Monte Carlo (MC) code. The imaging of polyacrylamide gel was accomplished by means of a co...

Modern radiation techniques aim on improved 3-dimensional (3D) spatial selectivity of the dose application sparing dose from organs-at-risk (e.g. IMRT with micro-multileaf collimation, γ-knife-, Brachyand heavy-ion therapy). The corresponding 3D-dose distributions exhibit high dose gradients above 4 Gy/mm, which are difficult to be investigated using standard single-point dosimetric detectors ...

Radiation dosimetry by Fricke gel was largely used, generally focused and optimized for radiotherapy applications therefore involving relative high dose levels. Fricke gel dosimetry has several advantages, like dose rate and LET almost independence, 3D mapping, among other. This work presents a novel Fricke gel dosimeter optimized for low dose levels. Several chemical composition were studied v...

Introduction: Multiple fields and presence of heterogeneities create complex dose distributions that need three dimensional dosimetry. In this work, we investigated MR-based MAGIC gel dosimetry as a three-dimensional dosimetry technique to measure the delivered dose to bladder and rectum in prostate radiation therapy. Materials and Methods: A heterogeneous slab phantom including bones was made....