The aim of this study is to determine the prevalence of unrecognized dyslipidaemia and a specific correlation between lipid values and age, gender or ethnic origin in the study population. This retrospective cross-sectional study included 311 subjects who had their lipid profiles checked for the first time in a private hospital in Dubai in a six month - period. The analysis shows an increased p...

conclusions this study supports the assumption that low glycemic index diet as well as metformin can positively affect metabolic syndrome components. background metabolic syndrome (mets) continues to be highly prevalent and contributes to a rapidly growing problem worldwide. the most important therapeutic intervention for metabolic syndrome is diet modification, an intervention whose efficacy h...

Approximately 50% of hemodialysis (HD) patients die from cardiovascular events. One of the main risk factors for cardiovascular events is hyperlipidemia. Progressive renal failure is associated with lipoprotein abnormalities and dyslipidemia. However, dyslipidemia may not appear as hyperlipidemia (a rise in plasma cholesterol and/or low-density lipoprotein (LDL)) in the majority of HD patients....

Serum Triglyceride and cholesterol were estimated by enzymatic method and routine method (Wybanga method) (10). HDL was determined by phosphotunstate/magnesium method fo l lowed by Wybanga method. (Serum is f ree f rom LDL, VLDL and Chlomicron). Low–density lipoprotein (LDL) and very low–density lipoprotein (VLDL) were found out by formula utilizing the values of cholesterol, Triglycerides, HDL...

Five different mouse monoclonal antibodies were raised against apoprotein B, the major protein in human low-density lipoproteins (LDL). Competitive binding studies suggested that these antibodies recognized four different epitopes on the lipoprotein particle. All antibodies bound to very-low-density and intermediate-density lipoproteins, which are the metabolic precursors of LDL and also contai...

Limitations in our ability to predict cardiovascular risk have fueled efforts to identify novel risk markers and to refine the measurement of traditional risk factors, such as low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C). Standard assays to evaluate LDL-C and HDL-C quantify the cholesterol content within the respective lipoprotein fraction. Howeve...

Background: Splenectomy is a common treatment for beta thalassemia. It not only eliminates many complications by reducing the need for blood transfusion, but also causes new complications that threaten the patientschr('39') health. The aim of this study was to determine if splenectomy could alter the lipid profile and glucose metabolism in beta thalassemia major patients. Methods: In this case-...

The hydromethylglutaryl coenzyme A (HMG CoA) reductase inhibitors, “statins,” have been remarkably effective in reducing low-density lipoprotein (LDL) cholesterol concentration, decreasing the incidence of coronary heart disease (CHD) and stroke, and extending survival (1–5). Statins inhibit the synthesis of cholesterol primarily in the liver. The hepatocyte, as its content of cholesterol decre...

Hepatic lipase (HL) is a key player in lipoprotein metabolism by modulating, through its lipolytic activity, the triglyceride (TG) and phospholipid content of apolipoprotein B (apoB)-containing lipoproteins and of high density lipoproteins (HDL), thereby affecting their size and density. A new and separate role has been suggested for HL in cellular lipoprotein metabolism, in which it serves as ...

This thesis is based on the following original articles, which are referred to in the text by their Roman numerals. acid content of LDL and lipoprotein metabolism in combined hyperlipidemia and primary moderate hypercholesterolemia. acid content of LDL and its relation to lipid concentrations and metabolism of LDL and cholesterol. Submitted. increases the sialic acid content of LDL in hyperchol...