نتایج جستجو برای: long chain acyl coa synthetase

تعداد نتایج: 1084410  

Journal: :The Biochemical journal 1979
R K Berge E Slinde M Farstad

The activities of long-chain acyl-CoA hydrolase (palmitoyl-CoA hydrolase, EC 3.1.2.2) and long-chain acyl-L-carnitine hydrolase, EC 3.1.1.28) in brown adipose tissue from cold-exposed and control guinea pigs were studied. Mitochondria from cold-exposed animals hydrolysed 21 nmol of palmitoyl-CoA/min per mg of protein and 1.3 nmol of palmitoyl-L-carnitine/min per mg of protein, and the specific ...

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2006
Chunze Li Raju Subramanian Sean Yu Thomayant Prueksaritanont

Formation of an acyl-CoA thioester has been proposed, but not directly demonstrated, to be a key step in mediating both lactonization and atypical beta-oxidation of 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors. Here, we describe studies to characterize formation of acyl-CoA thioesters in vitro in mouse liver preparations using the hydroxy acid form of simvastatin (SVA) as a model substra...

Journal: :The Journal of biological chemistry 2005
Concetta C DiRusso Hong Li Dina Darwis Paul A Watkins Johannas Berger Paul N Black

The fatty acid transport protein (FATP) family is a group of proteins that are predicted to be components of specific fatty acid trafficking pathways. In mammalian systems, six different isoforms have been identified, which function in the import of exogenous fatty acids or in the activation of very long-chain fatty acids. This has led to controversy as to whether these proteins function as mem...

Journal: :Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 2007

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