BACKGROUND AND PURPOSE Various laparoscopic devices have been described for suture anchoring during solidorgan parenchymal closure. Application of these devices expedites the closure of parenchymal defects and minimizes ischemia time. We compared different technologies as suture anchors for parenchymal closure. MATERIALS AND METHODS A tensometer was used to determine the amount of tension nec...

INTRODUCTION Nephron-sparing surgery for large renal masses is not considered a safe procedure because of high complication rate. We present our experience using expanded polytetrafluoroethylene (Gore-Tex) and Hem-O-Lok (Weck Clip) as hemostatic agents during open partial nephrectomy (OPN) to perform nephron-sparing surgery for large renal masses. MATERIALS AND METHODS Sixty patients underwen...

In patients with upper gastrointestinal bleeding (UGIB), identifying those with esophageal variceal hemorrhage prior to endoscopy would be clinically useful. This retrospective study of a large cohort of patients with UGIB used logistic regression analyses to evaluate the platelet count, aspartate aminotransferase (AST) to platelet ratio index (APRI), AST to alanine aminotransferase (ALT) ratio...

Y. M. Van der Linden, MD, Radiation Oncologist E. M. Noordijk, MD, Radiation Oncologist C. A. M. Marijnen, MD, Radiation Oncologist Department of Clinical Oncology P. D. S. Dijkstra, MD, Orthopaedic Surgeon Department of Orthopaedic Surgery H. M. Kroon, MD, Radiologist Department of Radiology J. J. Lok, PhD, Statistician Department of Medical Statistics Leiden University Medical Centre, Albinus...

MORRIS S. Y. JONG∗,‡, WEIQIN CHEN†,§, ALEX W. C. TSE∗,¶, FONG-LOK LEE∗,‖ and JIMMY H. M. LEE∗,∗∗ ∗Centre for the Advancement of Information Technology in Education The Chinese University of Hong Kong Shatin, N. T., Hong Kong †Department of Information Science and Media Studies University of Bergen Fosswinckelsgt. 6, Bergen, Norway ‡[email protected] §[email protected] ¶[email protected]...

Aspartate aminotransferase-to-platelet ratio (APRI), aspartate aminotransferase-to-alanine aminotransferase ratio (AAR), FIB-4, FI, King, Lok, Forns, and FibroIndex scores may be simple and convenient noninvasive diagnostic tests, because they are based on the regular laboratory tests and demographic data. This study aimed to systematically evaluate their diagnostic accuracy for the prediction ...

BACKGROUND Recent data suggest that noninvasive liver fibrosis indexes could be useful for predicting esophageal varices (EV) in cirrhotic patients. However, thus far, the diagnostic efficacy of these indexes in predicting portal hypertension (PH) in cirrhotic patients has been poorly evaluated. AIMS To evaluate the diagnostic efficacy of noninvasive liver fibrosis indexes in the diagnosis of...

Zuchang Gao 1, Cheng Siong Chin 2,*, Wai Lok Woo 3 and Junbo Jia 1 1 School of Engineering, Temasek Polytechnic, 21 Tampines Avenue 1, Singapore 529757, Singapore; [email protected] (Z.G.); [email protected] (J.J.) 2 School of Marine Science and Technology, Newcastle University, Newcastle upon Tyne NE1 7RU, UK 3 School of Electrical and Electronic Engineering, Newcastle University, Newcastle u...

Gutierrez, E., Seebacher, N., Arzuman, L., Kovacevic, Z., Lane, D., Richardson, V., Merlot, A., Lok, H., Kalinowski, D., Sahni, S., Jansson, P., Richardson, D. (2016). Lysosomal membrane stability plays a major role in the cytotoxic activity of the antiproliferative agent, di-2-pyridylketone 4,4-dimethyl-3thiosemicarbazone (Dp44mT). Biochimica et Biophysica Acta: international journal of bioche...