Aminoamide local anesthetics induce vasoconstriction in vivo and in vitro. The goals of this in vitro study were to investigate the potency of local anesthetic-induced vasoconstriction and to identify the physicochemical property (octanol/buffer partition coefficient, pKa, molecular weight, or potency) of local anesthetics that determines their potency in inducing isolated rat aortic ring contr...

This paper studies functional coefficient regression models with nonstationary time series data, allowing also for stationary covariates. A local linear fitting scheme is developed to estimate the coefficient functions. Consistency and asymptotic distributions of the estimators are obtained, showing different convergence rates for the stationary and nonstationary covariates. A two-stage approac...

This article treats the problem of learning a dictionary providing sparse representations for a given signal class, via l1 minimisation. The problem is to identify a dictionary Φ from a set of training samples Y knowing that Y = ΦX for some coefficient matrix X. Using a characterisation of coefficient matrices X that allow to recover any basis as a local minimum of an l1 minimisation problem, i...

A square splittered and unsplittered rod is placed in a turbulent boundary layer developed over a flat plate. The effect of the resulting disturbances on the local heat transfer coefficient is then studied. In both cases the square rod modifies the flow structure inside the boundary layer. As a result, a stagnation point, a jet and wake area are generated around the square rod, each making a co...

laminar free convection heat transfer from vertical and inclined arrays of horizontal isothermal cylinders in air was investigated experimentally and numerically. experiments were carried out using mach-zehnder interferometer and the fluent code was used for numerical study. investigation was performed for vertical and horizontal cylinder spacing from 2 to 5 and 0 to 2 cylinder diameters respec...

Nanofluids are stable suspensions of nanoparticles in conventional heat transfer fluids (base fluids) that exhibit better thermal characteristics compared to those of the base fluids. It is important to clarify various aspects of nanofluids behavior. In order to identify the thermal and hydrodynamic behavior of nanofluids flowing through non-circular ducts, in the present study the laminar flow...

Experiments were conducted to determine the influence of local vapor quality on local heat transfer coefficient in flow boiling in an array of microchannels. Additionally, the variation of local heat transfer coefficient along the length and width of the microchannel heat sink for given operating conditions was investigated over a range of flow parameters. Each test piece includes a silicon par...

A method is described for measuring the local drag coefficient on a long cylinder which exhibits vortex-induced vibration (VIV). Results are shown from a field experiment in which a long flexible pipe was instrumented with two-hundred and eighty fiber optic strain gauges. The measured local drag coefficients are compared to a commonly used drag coefficient prediction formula. The formula is sho...