Replisome assembly requires the loading of replicative hexameric helicases onto origins by AAA+ ATPases. How loader activity is appropriately controlled remains unclear. Here, we use structural and biochemical analyses to establish how an antimicrobial phage protein interferes with the function of the Staphylococcus aureus replicative helicase loader, DnaI. The viral protein binds to the loader...

Effective management of the vehicles plays an important role in transportation sector. There are some novel approaches in software engineering which can be used to dynamically control the trucks. One of the example technologies is multi-agent systems. Multi-agent-based technologies could be used for truck dispatching in real time. The trucks in such systems have their own transportation plan an...

The article presents the results of experimental studies performance a paddle feeder for continuous root crop loader. have obtained regression equations and graphical dependences productivity when changing angular speed blade rotation, forward movement with loader, as well radius cylindrical blades. show that loader working potatoes is in non-linear dependence on studied parameters described by...

The article is devoted to the study of influence carbon content in auger material on its wear during dehydration municipal solid waste garbage truck. Using method regression analysis, hyperbolic regularities screw depending for different values friction path were determined. Graphical dependences constructed, path, which confirms sufficient convergence obtained patterns. Carrying out additional...

Clamp-loader complexes are heteropentameric AAA+ ATPases that load sliding clamps onto DNA. The structure of the nucleotide-free Escherichia coli clamp loader had been determined previously and led to the proposal that the clamp-loader cycles between an inactive state, in which the ATPase domains form a closed ring, and an active state that opens up to form a "C" shape. The crystal structure wa...

The article covers the aspect related to assessment of efficiency truck operation in safety engineering for management supply chain security. publication contains an analysis functioning a selected transport company. concept operational was defined with taking into account standards European Union. essence securing delivery process example road also presented too. Then, and forecast made possib...