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one ef the most important innovations in the history ef traditional logic is the avicena's theory ef temporal modalities (.atm). althottgh) the basic concepts and elements ef this theory are fottnded in aristotelian and stoic-lvlegarian !0 gic) but as a independent lo,gical system, are devised on/y fry avicenna and were later developed and completed fry his followers. the atm theory contai...
Hexamethylmelamine (HMM) is metabolized by rat hepatic microsomal preparat ions to reactive species which covalent ly bind to microsomal protein and to calf thymus DNA added to microsomal incubation mixtures. Covalent binding to macromolecules is dependent on the presence of molecular oxygen and reduced nicot inamide adenine dinucleot ide phosphate and is catalyzed by cytochrome P-450 monooxyge...
15-Lipoxygenase-1 (15-LO-1) is involved in many pathological processes. The purpose of this study was to determine the potential role of 15-LO-1 in osteoarthritis (OA). The levels of 15-LO-1 expression were measured by western blotting and quantitative real-time PCR in articular cartilage from the OA rat models and OA patients. To further investigate the effects of 15-LO-1 on chondrocyte functi...
In a previous study, osteosarcoma cells expressing both 5-lipoxygenase (5-LO) and 5 lipoxygenase-activating protein (FLAP) synthesized leukotrienes upon A23187 stimulation (Dixon, R. A. F., R. E. Diehl, E. Opas, E. Rands, P. J. Vickers, J. F. Evans, J. W. Gillard, and D. K. Miller. 1990. Nature (Lond.). 343:282-284). Osteosarcoma cells expressing 5-LO but not expressing FLAP were unable to synt...
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