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Opioids generate free radicals that mediate protection in isolated cultured cardiomyocytes. We hypothesize that the nature of these radicals is nitric oxide, and that nitric oxide activates the protein kinase C (PKC) isoform. Through this signal transduction pathway, opiates protect cardiomyocytes during hypoxia and reoxygenation. Cell viability was quantified in chick embryonic ventricular myo...
Nitric Oxide Synthase (NOS) is believed to play a role in the development of the nervous system in the hawkmoth Manduca sexta. The enzyme produces Nitric Oxide (NO), which is a chemical messenger that triggers both intercellular and intracellular interactions. Specifically within Manduca sexta, NO is believed to help regulate the migration of particular cells during development of the antennal ...
Creativity – whether in humans or machines – is more than a matter of simple creation. To be “creative” implies an ability to do more than invent, but an ability to recognize and appreciate the inventions of others. After all, the ability to recognize surprising value in the efforts of others is the same ability we use to guide our own creative efforts. Solipsistic creativity is rare indeed, an...
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