Hepatocellular carcinoma can is often associated with hepatitis B infection. With localised tumours, liver resection can result in a cure. This case presents an unusual finding of concurrent hepatitis B and liver fluke infection with hepatocellular carcinoma in a 50 year old man from Thailand. The discussion illustrates difficulties of arriving at a diagnosis and ensuring appropriate surgical m...

Food borne trematodes (FBTs) are an assemblage of platyhelminth parasites transmitted through the food chain, four of which are recognized as neglected tropical diseases (NTDs). Fascioliasis stands out among the other NTDs due to its broad and significant impact on both human and animal health, as Fasciola sp., are also considered major pathogens of domesticated ruminants. Here we present a ref...

Water-borne disease fasciolosis with gastropods as intermediate hosts is still a burden for mankind, especially in tropical countries. Fasciolosis is caused by two trematodes Fasciola hepatica (the common liver fluke) and Fasciola gigantica (the large liver fluke) [1,2]. Fasciolosis is a common disease of many wild and domestic animals, especially sheep, goat, cattle[2,3]. The total global econ...

The prevalence of cholangiocarcinoma (CCA) in Southeast Asia is much higher than other areas of the world. Eating raw, fermented, or undercooked cyprinid fish, infected with the liver fluke, Opisthorchis viverrini sensu lato (sl), results in chronic biliary inflammation, periductal fibrosis, and increased cancer risk. There may be associated glomerulonephritis. The process of infection is diffi...

Livestock production around the world is impacted by liver fluke (Fasciola spp.) infection resulting in serious economic losses to beef, dairy and sheep industries with significant of about $90 million per annum Australia. Triclabendazole (TCBZ) most effective anthelmintic treatment available control infections; however, widespread emergence TCBZ resistance livestock threatens control. Alternat...

Flukes of ruminants are flatworm (trematodes) parasites living in the liver, fore stomachs or blood vessels, of which 40 different species may be present. Many other trematodes are parasites of fishes, poultry, carnivores and man. The liver fluke, Fasciola hepatica, was first described in France by Jean de Brie (1379), in his treatise on wool production and sheep management for the king Charles...

Fascioliasis is primarily an infection of livestock such as cattle and sheep, caused by the flat, brown liver fluke Fasciola hepatica. Humans are accidental hosts. The diagnosis of infection depends on suspicion. Radiologic findings are specific. Usually, Computed Tomography (CT) and other imaging studies show hypodense migratory lesions of the liver. The development of a chronic liver abscess ...

A survey incorporating field and abattoir studies was carried out on the prevalence of Dicrocoelium dendriticum in sheep and goats in the Kangra valley of Himachal Pradesh (India). Coprological studies on these migratory animals revealed that 8.1% of sheep and 4.1% of goats were positive for dicrocoeliosis, with a mean number of eggs per gram of faeces (EPG) of 702.1 for sheep and 566.7 for goa...

Livestock infection by the parasitic fluke Fasciola hepatica causes major economic losses worldwide. The excretory-secretory (ES) products produced by F. hepatica are key players in understanding the host-parasite interaction and offer targets for chemoand immunotherapy. For the first time, subproteomics has been used to compare ES products produced by adult F. hepatica in vivo, within ovine ho...