نتایج جستجو برای: lipotoxicity
تعداد نتایج: 1097 فیلتر نتایج به سال:
Cellular free fatty acids are toxic for cells, which also contributes to the pathogenesis of cardiovascular diseases and metabolic syndrome. Cells handle so-called lipotoxicity resulting by an excess of free fatty acids via triglyceride accumulation [1]. This happens not only in adipocytes, but in all cells; the amount and size of lipid droplets in adipocytes is much bigger, as these cells are ...
BACKGROUND The mechanisms of right ventricular (RV) failure in pulmonary arterial hypertension (PAH) are poorly understood. Abnormalities in fatty acid (FA) metabolism have been described in experimental models of PAH, but systemic and myocardial FA metabolism has not been studied in human PAH. METHODS AND RESULTS We used human blood, RV tissue, and noninvasive imaging to characterize multipl...
Polycystic ovary syndrome (PCOS) is a common condition affecting women of reproductive age. This disorder is characterized by hyperandrogenism and anovulation and is frequently associated with comorbidities such as infertility, metabolic syndrome, type 2 diabetes, and cardiovascular risk factors. Although the causes of PCOS are unknown, this review focuses on the most accepted theory involving ...
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