tilmicosin (tlm) is an important antibiotic in veterinary medicine with low bioavailability and safety. this study aimed to formulate and evaluate physicochemical properties, storage stability after lyophilization and antibacterial activity of three tlm-loaded lipid nanoparticles (tlm-lnps) including solid lipid nanoparticles (slns), nanostructured lipid carriers (nlcs) and lipid-core nanocapsu...

background: cancer has the highest disease-related mortality rate in iran. reduced activity of paraoxonase reported in patients with cancer may be due to a reduction in its antioxidant properties and a subsequent increased risk of developing cancer. we aimed to assess antioxidant and oxidative status in patients with cancer through measuring the activity of pon1 as an antioxidant enzyme and det...

background and aims. oral lichen planus is a common chronic inflammatory disease of the oral mucosa with malignant potential, pathogenesis of which is not still well known. free radicals and reactive oxygen species can play an important role in the pathogenesis of oral lichen planus. the aim of this study was to investigate salivary oxidative stress and antioxidant systems in patients with oral...

background: bilateral salpingo-oophorectomy in women may lead to metabolic consequences in patients. this study was performed to determine the glucose tolerance and lipid profile after menopause resulting from bilateral salpingo-oophorectomy. methods: from september 2011 to march 2013, 31 women participants aged 46-52 years who underwent hysterectomy and bilateral salpingo-oophorectomy for beni...

background: multiple sclerosis (ms) is one of the most prevalent of nerves system disease. ms is a chronic neurodegenerative disorder. nutrition and diet are effective factors for prevention and treatment in ms, however finding are controversial. the aim of this study was investigation of dietary pattern of fat consumption and its relationship with lipid profiles crp level in ms patient.  metho...

conclusions in a current study based on increasing maternal age, the hdl-c level in cord blood was decreased which is an independent risk factor for cvds in adulthood. results a statistically significant negative correlation was observed between cord blood hdl-c and maternal age (r = -0.18, p <0.01). there was no relationship between other lipids and lipoproteins with maternal age. our findings...

conclusions the results suggest that physical activity improves metabolic parameters, which interfere in the development of fatty liver and has a protective role against the development of nafld. results statistical analysis demonstrated that the training group had significant changes in weight, bmi, tc, tg, ldl, vldl, hdl/ldl, tc/ hdl, ast and alt, whereas there was no significant change in hd...

abstract:introduction: racial and environmental differences in communities leading cause of differences in serum lipids. it can be said this study aimed in assessing percentile curves of serum lipid profile about 6-18 years old students of birjand.method: the present cross-sectional study was done on 4168 students of birjand aged 6-18 years. they were classified into three age groups 6-10 and 1...

conclusions ehp was able to both reduce ldl-ch and to significantly decrease markers of oxidative stress and lipid peroxidation induced by hyperlipidemia. therefore, this herb, as a new pharmacological component, could be used to reduce certain blood lipids, lipid peroxidation, and aminotransferase markers. materials and methods thirty-two male rats weighting 200 ± 10 g were randomly divided in...

metabolic syndrome (mets) is characterized by a cluster of cardiovascular risk factors that include: abdominal obesity, dyslipidaemia, hypertension, insulin resistance and impaired glucose tolerance. recent genome wide association studies have identified several susceptibility regions involved in lipid metabolism that are also associated with mets. we have explored the association of 9 genetic ...