Diepoxides of linolenic acid were found to be chemoattractants. The concentration that produces 50% of maximal chemotaxis was 4.5 10(-7) mol/l for human neutrophils when investigated in a chemotaxis test based on the method of spectrophotometric determination of myeloperoxidase activity with buffers containing bovine serum albumin. Leukotriene B4 was used as positive control. The concentration ...

In both plants and animals pathways exist for the conversion of oleic acid to polyenoic acids (1, 2), but these pathways lead to different end products in the two kingdoms. In green plants the double bond system is extended toward the methyl end of the molecule to form linoleic and linolenic acids (9,12, lBoctadecatrienoic acid) (1,3,4). The ciliated protozoa, the amoebae, and some other animal...

BACKGROUND Epidemiologic data suggest that diet is a risk factor in the etiology of gastric cancer. However, the role of dietary fatty acids, a modifiable risk factor, remains relatively unexplored. OBJECTIVE The objective of this study was to determine the association of plasma phospholipid fatty acid concentrations, as biomarkers of exogenous and endogenously derived fatty acids, with the r...

I . The fatty acid compositions of the plasma cholesteryl esters, phospholipids, triglycerides and unesterified fatty acids were determined in three sheep at various times after they had been given intra-abomasal infusions of emulsions of linseed oil, maize oil or linoleic acid. 2. The concentrations of linolenic acid or linoleic acid in the plasma triglycerides began to increase 1.5 h after in...

Reactive oxygen species (ROS) are elevated by metabolic changes in diabetes, including autoxidation and increased advanced glycation. Endogenous protection by the glutathione redox cycle is also compromised by the competing NADPH requirement of elevated polyol pathway flux. Antioxidant treatment strategies prevent or reverse nerve conduction velocity (NCV) deficits in diabetic rats. These inclu...

High oleic soybean (HOSBO) and low linolenic acid soybean (LLSBO) oils were evaluated individually and in a 1:1 blend along with cottonseed oil (CSO) to determine frying oil stabilities and the flavor quality and stability of potato chips. Potato chips were fried in the oils for a total of 25 h. Potato chips and oils were sampled periodically for sensory data, gas chromatographic volatile compo...

Depending on the variety, flax (Linum usitatissimum L.) provides an oil rich in omega-3 acids (especially 50% ?-linolenic acid) with proven health properties, and is used as a raw industrial material. Alpha-linolenic acid polyunsaturated fatty easily subject to oxidative transformation. The auto-oxidation of main process contributing off-flavor, color loss, change nutritional value oil. We six ...

This study examined the effects of dietary alpha-linolenic acid deficiency followed or not by supplementation with phospholipids rich in n;-3 polyunsaturated fatty acid (PUFA) on the fatty acid composition of total phospholipids in 11 brain regions. Three weeks before mating, mice were fed a semisynthetic diet containing both linoleic and alpha-linolenic acid or deficient in alpha-linolenic aci...

Background: Animal models suggest that n-3 fatty acids inhibit prostate cancer proliferation, whereas n-6 fatty acids promote it, but epidemiologic studies do not uniformly support these findings. Methods: A nested case-control study was conducted among 14,916 apparently healthy men who provided blood samples in 1982. Blood fatty acid levels were determined for 476 men diagnosed with prostate c...

The influence of culture temperature and the concentration of sodium nitrate (NaNO3) on the gas-chromatographic profile of the fatty acids of the filamentous cyanobacterium Spirulina platensis was evaluated. We found that temperature was the most important factor and that the greatest amount of gamma-linolenic acid (GLA) was obtained at 30 degrees C, the fatty acid profile of the Spirulina cult...