نتایج جستجو برای: like growth factor

تعداد نتایج: 2001391  

Journal: :The Journal of endocrinology 2000
J W van Neck E M Berghout L Vinter-Jensen C A Groffen V Cingel N F Dits S L Drop A Flyvbjerg

Systemic administration of epidermal growth factor (EGF) in neonatal rats results in reduced body weight gain and decreased circulating levels of IGF-I, suggesting its involvement in EGF-induced growth retardation. We investigated the effect of EGF and/or IGF-I administration for 7 days on circulating IGF-I and IGFBP levels and hepatic and renal IGF-system mRNA expression profiles in adult fema...

Journal: :Diabetes 2002
Patricia Serradas Luis Goya Matthieu Lacorne Marie-Noëlle Gangnerau Sonia Ramos Carmen Alvarez Ana-Maria Pascual-Leone Bernard Portha

At late fetal age (21.5 days postcoitum [dpc]), GK rats present a severely reduced beta-cell mass compared with Wistar rats. This anomaly largely antedates the onset of hyperglycemia in GK rats. Thus, the beta-cell mass deficit could represent the primary defect leading to type 2 diabetes in the adult. The aim of this work was to investigate, in GK fetuses at the end of fetal age (21.5 dpc), wh...

Journal: :iranian journal of pathology 2008
mitra mehrazma khadijeh arjomandi rafsanjani behzad torkamanipoor

background and objective: vascular endothelial growth factor (vegf) and its receptors (vegf-r1 and r2) are major regulators of angiogenesis. this study was designed to assess serum levels of vegf and vegf-r1 and their prognostic significance in newly diagnosed childhood acute leukemia. materials and methods: for this purpose, vegf and vegf-r1 were determined using enzyme linked immuno-sorbant a...

Journal: :iranian journal of biotechnology 2008
maryam jazayeri abdolamir allameh masoud soleimani seyed hamid jazayeri saeid kaviani

human bone marrow derived mesenchymal stem cells (hbmscs) have the potential to differentiate into cells such as adipocyte, osteocyte, hepatocyte and endothelial cells. in this study, the differentiation of hbmscs into endothelial like-cells was induced in presence of vascular endothelial growth factor (vegf) and insulin-like growth factor (igf-1). the differentiated endothelial cells were exam...

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