نتایج جستجو برای: ligand urea
تعداد نتایج: 144786 فیلتر نتایج به سال:
The androgen receptor plays a critical role in the progression of prostate cancer. Here, we describe targeting the prostate-specific membrane antigen using a lipid nanoparticle formulation containing small interfering RNA designed to silence expression of the messenger RNA encoding the androgen receptor. Specifically, a Glu-urea-Lys PSMA-targeting ligand was incorporated into the lipid nanopart...
Five rare earth complexeslanthanum(III),praseodymium(III),neodymium(III), samarium(III) and europium(III) have been synthesized from Schiff base ligand (N,N-bis (2-hydroxy-1-naphthylidene) acetylhydrazone). The complexes were characterized based on elemental analysis, molar conductance, ultraviolet, infrared, mass, thermogravimetric and powder X-ray diffraction studies. Infrared spectra sug...
macrocyclic heterobinuclear zn(ii)–cu(ii) complexes with phenol based dicompartmental ligands possessing contiguous hexa- and penta-coordination sites were prepared by a stepwise procedure. the ligands include similar n4o2 and dissimilar n(imine)3o2 and n(amine)3o2 coordination sites sharing two phenolic oxygen atoms. the six-coordination site comprises two pyridyl pendant arms on the amine nit...
Objective: Many methods can be found in literature for the synthesis a Oxazines and Thiazines. Few are reported one-pot multi component cyclo-condensation of an alkayane urea / Thiourea Aldehyde to 2- amino-4H-1, 3-Oxazines or Different catalysts like Trifluoro-acetic acid, glacial acetic acid under reflux condition Mandal Co-workers have utilized perchloric (HClO4) supported on silica gel as c...
A combined ligand and structure-based drug design approach provides a synergistic advantage over either methods performed individually. Present work bestows a good assembly of ligand and structure-based pharmacophore generation concept. Ligand-oriented study was accomplished by employing the HypoGen module of Catalyst in which we have translated the experimental findings into 3-D pharmacophore ...
The synthesis and analytical applications of the new heterocyclic ligand are described. The complexation reaction of the ligand with some cations was studied in aqueous methanol at room temperature using the spectrophotometric method. Results revealed that only the absorption spectra of the Fe (III)–ligand complex show a high redshift of the absorption maximum in the aqueous methanol soluti...
the nutritional value of cereal straw can be increased using urea treatments as a source of ammonia. the conventional urea treatment process for cereal straw is a laborious and time-consuming task. it is essential to facilitate or eliminate part of the procedure with the use of machinery. this study examines the mechanical urea treatment of wheat straw and compares chemical components and diges...
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