FRET measurements can provide dynamic spatial information on length scales smaller than the diffraction limit of light. Several methods exist to measure FRET between fluorophores, including Fluorescence Lifetime Imaging Microscopy (FLIM), which relies on the reduction of fluorescence lifetime when a fluorophore is undergoing FRET. FLIM measurements take the form of histograms of photon arrival ...

Researchers have begun to use formal architectural speci cation as a basis on which to develop testing techniques. These techniques promise to improve the development process by uncovering defects early. However, few of these techniques consider the ways in which software architecture can be used to facilitate (or misused to hinder) e ective regression testing and analysis of evolving systems. ...

Quality management is very important for many manufacturing industries. Process capability analysis has been widely applied in the field of quality control to monitor the performance of industrial processes. Hence, the lifetime performance indexC L is utilized to measure the performance of product, where L is the lower specification limit. This study constructs a Bayesian estimator of C L under...

BACKGROUND This study was conducted to determine the prevalence of HIV antibody testing and associated factors among heterosexual sexually transmitted disease (STD) clinic attendees in China. METHODS A self-administered questionnaire was administered among 823 attendees of 4 STD clinics of Zhejiang Province, China in October to December 2007. Psychosocial and behavioural factors associated wi...

BACKGROUND The American Cancer Society (ACS) guidelines for screening with breast magnetic resonance imaging (MRI) recommend MRI for women who have a lifetime risk > or = 20% of developing breast cancer. Genetic testing for breast cancer gene (BRCA) mutations is offered to women who have a risk > or = 10% of carrying a mutation. The objectives of the current study were 1) to identify the number...

OBJECTIVES Human papillomavirus (HPV) testing is not widely used for triage of equivocal Pap smears or primary screening in Québec, Canada. Our objective was to evaluate the cost-effectiveness of cervical cancer screening strategies utilizing HPV testing. METHODS We used a lifetime Markov model to estimate costs, quality of life, and survival associated with the following strategies: 1) cytol...

Process capability analysis has been widely applied in the field of quality control to monitor the performance of industrial processes. In practice, lifetime performance index CL is a popular means to assess the performance and potential of their processes, where L is the lower specification limit. Nevertheless, many processes possess a non-normal lifetime model, the assumption of normality is ...

The lifetime risk of acquiring HIV infection in many rural as well as urban areas of southern Africa is currently as high as two-in-three. For women, much of this risk still accrues rapidly at young ages despite high levels of knowledge about HIV/AIDS. Thus, programmes that are more participatory and address underlying structural and community-level factors appear to be essential. We use cross-...

in this paper, we consider an  i.e., multiple step-stress accelerated life testing (alt) experiment with unequal duration of time . it is assumed that the time to failure of a product follows rayleigh distribution with a log-linear relationship between stress and lifetime and also we assume a generalized khamis-higgins model for the effect of changing stress levels. taking into account that the...