نتایج جستجو برای: leukocyte therapy

تعداد نتایج: 684252  

2017
Efthymios Arvanitidis Sergio Bizzarro Elena Alvarez Rodriguez Bruno G. Loos Elena A. Nicu

BACKGROUND Platelets from untreated periodontitis patients are hyper-reactive and form more platelet-leukocyte complexes compared to cells from individuals without periodontitis. It is not known whether the improvement of the periodontal condition achievable by therapy has beneficial effects on the platelet function. We aimed to assess the effects of periodontal therapy on platelet reactivity. ...

Journal: :Blood 2012
Camila Bononi Almeida Christoph Scheiermann Jung-Eun Jang Colette Prophete Fernando Ferreira Costa Nicola Conran Paul S Frenette

Inhibition of leukocyte adhesion to the vascular endothelium represents a novel and important approach for decreasing sickle cell disease (SCD) vaso-occlusion. Using a humanized SCD-mouse-model of tumor necrosis factor-α-induced acute vaso-occlusion, we herein present data demonstrating that short-term administration of either hydroxyurea or the phosphodiesterase 9 (PDE9) inhibitor, BAY73-6691,...

Journal: :Blood 1988
G Andreu J Dewailly C Leberre M C Quarre M L Bidet R Tardivel L Devers Y Lam E Soreau C Boccaccio

HLA immunization is a common complication of transfusion therapy in 30% to 60% of oncohematologic patients. Evidence shows that leukocytes present in cellular blood products are the main component involved in the occurrence of HLA immunization, and several studies showed that leukocyte-poor blood products are less able to induce it. However, leukocyte-poor platelet concentrates obtained by conv...

Journal: :Investigative ophthalmology & visual science 2012
Shintaro Nakao Mitsuru Arima Keijiro Ishikawa Riichiro Kohno Shuhei Kawahara Masanori Miyazaki Shigeo Yoshida Hiroshi Enaida Ali Hafezi-Moghadam Toshihiro Kono Tatsuro Ishibashi

PURPOSE Anti-VEGF-A antibody (Ab) (e.g., bevacizumab, ranibizumab) is widely used as a treatment against retinal angiogenesis and edema. The purpose of this study was to evaluate whether intravitreal anti-VEGF Ab injection modulates inflammatory cells in retinal angiogenesis. METHODS To investigate whether intravitreal bevacizumab injections affect the number of inflammatory cells in prolifer...

Journal: :Reproductive health of woman 2021

Pathological discharge from the genital tract and other signs of discomfort external genitalia are a common cause visit to gynecologist. The these disorders in most cases is vulvovaginal infection, accompanied (vaginitis) or not (vaginosis) by leukocyte reaction. Methods for treating infection predominantly local therapy systemic agents with highly selective antimicrobial activity. Since signif...

Journal: :American journal of physiology. Heart and circulatory physiology 2009
Hao-Liang Xu Francesco Vetri Hae-Kyung Lee Shuhua Ye Chanannait Paisansathan Lizhen Mao Fulong Tan Dale A Pelligrino

In this study, we tested the hypothesis that the documented transformation of 17beta-estradiol (E2) from a counterinflammatory hormone in nondiabetic (ND) rats to a proinflammatory agent in rats with diabetes mellitus (DM) is due to an enhanced contribution from the receptor for advanced glycation end products (RAGE). Rhodamine 6G-labeled leukocytes were observed through a closed cranial window...

Journal: :iranian red crescent medical journal 0
hamidreza taghipour trauma research center, baqiyatallah university of medical sciences, tehran, ir iran hamid shafiei cardiac surgery ward, baqiyatallah hospital, tehran, ir iran omid assar cardiovascular research center, baqiyatallah university of medical sciences, tehran, ir iran; cardiovascular research center, baqiyatallah university of medical sciences, tehran, ir iran. tel: +98-2122569602, fax: +98-2122569602 mohammad saaid ghiasi jamaran heart hospitals, tehran, ir iran

conclusions systemic arterial leukocyte filtration reduces the intubation time but has no other beneficial effect on the outcome of patients undergoing cabg or valve surgery. results the postoperative intubation time was significantly shorter in patients with leukocyte filters (0.014). there was no significant difference between two groups regarding other outcome relatedvariables. patients and ...

Journal: :Actas dermo-sifiliograficas 2009
L Pérez-Carmona A Harto-Castaño E Díez-Recio P Jaén-Olasolo

Extracorporeal photochemotherapy or photopheresis is an immunomodulatory therapy that combines leukapheresis with phototherapy. Blood from the patient is processed to give a leukocyte-rich plasma, which is then treated ex vivo with a photosensitizer and ultraviolet A radiation before reinfusion back into the patient. The exact mechanism of action of photopheresis has not been fully elucidated a...

Journal: :European journal of immunology 2005
Christopher M Kirton Marja-Leena Laukkanen Antti Nieminen Marika Merinen Craig M Stolen Kathryn Armour David J Smith Marko Salmi Sirpa Jalkanen Michael R Clark

Human vascular adhesion protein-1 (VAP-1) is a homodimeric 170-kDa sialoglycoprotein that is expressed on the surface of endothelial cells and functions as a semicarbazide-sensitive amine oxidase and as an adhesion molecule. Blockade of VAP-1 has been shown to reduce leukocyte adhesion and transmigration in in vivo and in vitro models, suggesting that VAP-1 is a potential target for anti-inflam...

B Sadeghi , F Atashrazm , F Babahoseini , H Abolghasemi , H Sammak , M Aghaiipour , M Nikougoftar , P Zarei , S Rahmani ,

Introduction: Leukocytes causing a wide variety of side effects after transfusion are present in all blood products prepared by standard methods. As a consequence, the use of filter technology for leukoreduction has been widely practiced .According to AABB accreditation in 1996, leukoreduced blood components must contain less than 5×106 leukocytes per unit, but sometimes this value is higher ev...

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