background: studies have shown that obese individuals are at increased risk of breast cancer development and poorer prognosis. leptin, an adipose tissue-derived hormone, has pro-inflammatory and proliferative effects and a well-established association with several comorbidities of obesity. this study was designed and conducted to compare the serum levels of leptin in patients with malignant and...

objective(s):the aim of the study was to investigate the relationship between insulin resistance (ir) and leptin (lep) gene polymorphisms in peritoneal dialysis (pd) patients. materials and methods: from july 1, 2011 to august 1, 2011, patients who received chronic pd were chosen and divided into three groups (dm, high homr-ir, and low homr-ir). two pcr products of lep were sequenced and aligne...

  Objective(s): Leptin is a hormone secreted by adipose tissue and is involved not only in the regulation of feeding and energy expenditure, but also its role in memory enhancement has been demonstrated as well. The partial transfer of leptin across the blood-brain barrier in obese individuals causes leptin resistance and prevents leptin reaching brain. On the other hand, studies have show...

background: leptin and adiponectin are the two key metabolic hormones secreted from adipocytes to control food intake and energy expenditure. the action of both hormones in regulation of gonadotropin releasing hormone (gnrh) secretion from the hypothalamus is mediated through kisspeptins. kisspeptins are products of kiss-1 gene. leptin and adiponectin are modulators of kiss-1 expression in the ...

background: leptin is a polypeptide hormone secreted by white adipose tissue in proportion to body energy. although the participation of leptin in female reproduction is well established any role in male reproductive function is at best tenuous. objective: the objective of this study was to compare the leptin concentration in human seminal plasma and then the relationships between seminal lepti...

Background: The present study aimed to investigate the presence of leptin mRNA transcript in epididymal spermatozoa of Holstein cattle by RT-PCR analysis. Materials and Methods: To collect sperm from epididymis, the whole testes of three adult Holstein bulls were quickly removed after slaughtering. Samples were transferred to the laboratory on ice and subsequently the epididymal contents were c...

background obesity is a medical problem in survivors of childhood acute lymphoblastic leukemia. obesity is associated with many complications, so it is important to investigate the respective etiology. leptin is a protein synthesized in the fatty tissue and is effective in the control of obesity. survey of leptin in acute lymphoblastic leukemia (all) survivors could be helpful in controlling ob...