Introduction: According to evidence, Early-Life Stress (ELS), mood disorders, and medical comorbidities, i.e.  Irritable Bowel Syndrome (IBS), are correlated; however, the direct contribution of ELS to IBS manifestations is less understood. The current study aimed at evaluating the effect of voluntary exercise on the mitochondrial dysfunction of the bowel fibroblasts, following the confirmation...

background: asthma is a common condition in general medical practice, and it accounts for about 1% of all ambulatory hospital visits. nowadays, hospitalization rates for asthma have actually been increased in some demographic subgroups despite recent advances in treatment. understanding the underlying factors that contribute to hospitalization and especially duration of the hospitalization of a...

Intestinal adaptation after extensive small bowel resection results in mucosal hypertrophy and an increased capacity of the remaining small intestine to absorb solutes and water. We tested the ability of the adapted rat ileum to respond to a secretory stimulus, cholera toxin. Six weeks after 50% jejunal resection (short gut) or sham operation water and solute transport were measured in a 16 cm ...

BACKGROUND Type III and IV jejunoileal atresias are associated with loss of significant length of the gut and can lead to short gut syndrome if further resection of proximal dilated gut is done. We modified the anastomotic technique so that proximal dilated segment of the gut is not resected as to prevent short gut syndrome. MATERIAL AND METHODS Medical Record of patients of Type III and IV j...

Gut-associated lymphoid tissues (GALTs) comprise key intestinal immune inductive sites, including the Peyer’s patches of small intestine and different types isolated follicle (ILF) found along length gut. Our understanding human GALT is limited due to a lack protocols for their isolation. Here we describe technique that, uniquely among cell isolation protocols, allows identification all GALT, a...

Background: Colorectal cancer is the second most common cancer in the world which is mainly caused by epigenetic and environmental factors. Among these epigenetic factors, gut microbiota is an important one. Although it has not been proved a unique group of bacteria correlated with colorectal cancer, these findings have generally demonstrated differences between healthy and disease gut microbio...

introduction: the important of comparing performance of hospitals using hospital indicators, has been made the necessary of utilizing of the application model inevitable. this study aimed to compare hospital performance key indicators simultaneity. methods: in this descriptive cross sectional and retrospective study, 31 hospitals of isfahan university of medical sciences were evaluated in 2007....

objectives the purpose of this study was to determine the types of fall-related injuries and the related risk factors in the elderly population of qom province, iran. patients and methods this retrospective study was performed on 424 elderly people (65 years and over) referred to shahid beheshti hospital, qom, iran, due to falls between 2010 and 2012. the icd-10 codes of external causes of inju...

Caenorhabditis elegans gut granules are lysosome-related organelles with birefringent contents. mrp-4, which encodes an ATP-binding cassette (ABC) transporter homologous to mammalian multidrug resistance proteins, functions in the formation of gut granule birefringence. mrp-4(-) embryos show a delayed appearance of birefringent material in the gut granule but otherwise appear to form gut granul...