A discriminator circuit uses dual current sources charging a capacitor to produce an output timing edge a fixed time after the starting corner of the input pulse, nearly independent of risetime and threshold setting. Performance with artificial and real pulses in the microsecond range is described. Background Obtaining a good timing information from slow-rising pulses is an old problem in pulse...

Establishment of a neuronal system requires proper regulation of the F-actin-rich leading edges of migrating neurons and neurite growth cones. A new study shows that RhoG signals through the multi-domain protein anillin to stabilize F-actin in these structures.

Intravenous lipid emulsion therapy was introduced as a treatment for local anesthetic toxicity it has shown couple of reversing and therapeutic efficacies for a number of different drug toxicities. In recent papers many different applications of Intralipid or oil containing products-Lipid Emulsion-have successfully experimented in critical care patients. In 1998 Dr. Weinberg began working on th...

Stem cells, by virtue of their defining property of self-renewal, represent an unlimited source of potentially functional human cells for basic research and regenerative medicine. Having validated the feasibility of cell-based therapeutic strategies over the past decade, mostly through the use of rodent cells, the stem cell field has now embarked upon a detailed characterization of human cells....

Future hypersonic vehicles are likely to use sharp leading edges on wings and engine inlets to reduce drag. The radius of curvature associated with such structures may be one centimeter or less. The very small size leads to high heating rates that can be accommodated using advanced materials. An additional aspect of the small size concerns the basic gas dynamics. At such small scales, the conti...

An experimental investigation was performed with two aims: (1) to clarify the existence of the dual leading-edge vortices (i.e. two vortices with the same sense of rotation located close to the leading edge above the leeward wing surface) observed on flapping wings in previous studies; (2) to study systematically the influences of kinematic and geometric parameters on such a vortical structure....