Graphene oxide-iron oxide (GO-Fe3O4) nanocomposites were synthesised by co-precipitating iron salts onto GO sheets in basic solution. The results showed that formation of two distinct structures was dependent upon the GO loading. The first structure corresponds to a low GO loading up to 10 wt%, associated with the beneficial intercalation of GO within Fe3O4 nanoparticles and resulting in higher...

Antiangiogenic therapy can produce transient tumor regression in glioblastoma (GBM), but no prolongation in patient survival has been achieved. We have constructed a nanosystem targeted to tumor vasculature that incorporates three elements: (i) a tumor-homing peptide that specifically delivers its payload to the mitochondria of tumor endothelial cells and tumor cells, (ii) conjugation of this h...

AIMS To evaluate the feasibility of loading resting monocytes/macrophages by intravenous (i.v.) injection of fluorescent iron oxide nanoparticles prior to injury and tracking of these cells in the very same animal to myocardial infarction (MI) by magnetic resonance imaging (MRI) and optical imaging. METHODS AND RESULTS Rats were injected with fluorescent iron oxide nanoparticles (10 mg/kg) (n...

Background: Angiotensin converting enzyme (ACE) upregulation in stromal cells of joints affected by rheumatoid arthritis may lead to higher tissue angiotensin II that is a vasoconstrictor and mitogen factor. To date, the role of angiotensin II on regulating blood flow in inflamed joints has not been studied. Methods: Acute and chronic joint inflammation was induced in rabbits by intra-articular...

background: increased impervious surfaces in urban areas not only increase runoff volume and peak flow, but also worsen urban storm water pollution. the polluted runoff has many adverse impacts on human life and environment. the purpose of this study was to investigate and compare the efficiency of sand columns coated with nanoparticles of iron oxide in the presence and absence of a magnetic fi...

in this study, magnetic iron oxide nanoparticles (fe3o4) with the size range of 20-30 nm were prepared by the modified controlled chemical co-precipitation method from the solution of ferrous/ferric mixed salt-solution in alkaline medium. in this process polyethylene glycol was used as a surfactant to prevent the solution from agglomeration. the prepared magnetic nanoparticles were characterize...