AIMS Rosuvastatin is more efficacious than other statins in lowering low-density lipoprotein cholesterol (LDL-C). Studies showing higher blood levels in Asians have resulted in concerns regarding increased adverse drug reactions. This study aimed to evaluate the efficacy and safety of rosuvastatin in hypercholesterolemic Asian patients. METHODS This retrospective observational study was condu...

BACKGROUND Few studies have been conducted that make comparisons between traditional measures of cholesterol and cholesterol subfractions, and only one study has compared low-density lipoprotein cholesterol (LDL-C) particle number, LDL-C particle size and LDL-C among end-stage renal disease (ESRD) patients. The purpose of this study was to examine the relationships between cholesterol measures ...

Calculated low-density lipoprotein cholesterol (LDL-C) concentrations determined from the Friedewald equation have a large intraindividual CV, in part because the calculation incorporates the variability of cholesterol, high-density lipoprotein cholesterol (HDL-C), and triglyceride measurements. We studied whether a new assay that measures LDL-C directly will reduce this variability and reduce ...

Background: The superiority of TG/HDL-C and LDL-C/HDL-C ratios in predicting  CVD risk is a matter of debates. Thus, the objective of this study was to compare TG/HDL-C and LDL-C to HDL-C ratios in predicting the risk of CVD events. Methods: In a population-based cross-sectional study, 567 representative participants aged 40 years or older were entered in the study in Babol, North of Iran. The...

Regular physical activity with adequate intensity, according to WHO recommendations, can prevent various chronic diseases, such as heart disease, diabetes mellitus, cancer, and bone disease. Physical improve lipid profil: triglycerides, total cholesterol, HDL cholesterol (HDL-C), LDL (LDL-C). The aim of this study was compare profiles, which include levels (LDL-C) at different activity: low, me...

Hiperkolesterolemia familial (FH) merupakan kelainan autosomal dominan yang ditandai dengan kadar low-density lipoprotein kolesterol (LDL-C) tinggi pada plasma. Bahaya resiko kejadian kardiovaskular dan tingginya angka prevalensi menjadikan hiperkolesterolemia beban penyakit harus segera ditangani. Modifikasi gaya hidup memang tatalaksana awal namun banyak dari pasien FH membutuhkan terapi farm...

The study was devoted to the of prevalence hypercholesterolemia (hyper-Chol) and low density lipoproteins (hyper-LDL-C) against background abdominal obesity (AO) in a population aged 25–44 years Novosibirsk. Material methods . A crosssectional survey Novosibirsk (Russia) carried out. 1415 people were examined, including 670 men (47.3 %) 745 women (52.7 %), pregnant or being on maternity leave n...

OBJECTIVES We assessed relations of low-density lipoprotein (LDL) particle number (LDL-P) and LDL particle size as measured by nuclear magnetic resonance spectroscopy with LDL cholesterol (LDL-C) and the risk of future coronary artery disease (CAD). BACKGROUND Whereas LDL-C is an established risk factor for CAD, its discriminative power is limited. Measuring LDL-P and size may have stronger a...