We studied the influence of PON1 on metabolic alterations induced by oxidized LDL when incubated with endothelial cells. HUVEC cells were incubated with native LDL, oxidized LDL, oxidized LDL plus HDL from wild type mice, and oxidized LDL plus HDL from PON1-deficient mice. Results showed alterations in carbohydrate and phospholipid metabolism and increased apoptosis in cells incubated with oxid...

Introduction. Cannabis sativa is a source of oil seeds for pharmaceutical, cosmetic, and food uses. Objective. The aim this study to evaluate the hypolipidemic effect hemp seed (HSO) obtained from local ecotype called “Beldiya.” Methods. extraction HSO was carried out by cold press method. Then, fatty acid tocopherol composition analyzed, respectively, GC-FID HPLC. activity at dose 3.5 7 mg/kg ...

The role of lipoprotein lipase (LPL) in the generation of low density lipoprotein (LDL) and high density lipoprotein (HDL) was investigated. Intravenous injections of high titer goat antiserum against highly purified chicken LPL into fasted roosters quantitatively blocks the removal of plasma VLDL triglyceride (1976. J. Lipid Res. 17: 498-505). Analyses of the chemical components of lipoprotein...

Abstract This study aimed to investigate the effects of dietary supplementation with modified-hen-egg-yolk on plasma lipids and lipoprotein profiles in rats. During four-week-experiment, 64 Wistar rats were divided into four groups 16 (eight both sexes), fed commercial rat food (group C); containing 70% mixture 30% freshly cooked egg yolk originating from laying hen eggs 3% fish oil F); palm ol...

background & aim: hyper lipidemy is one of the main factors in progressing cardiovascular diseases. thymus deanensis celak and satureja bachtiarica bunge are medicinal herbs which are used in folklore medicine in iran. in this research, hypolipidemic effects of essential oils of these herbs in rats fed with a fatty diet were investigated.experimental: 40 male and femade adult rats (20 rats ...

introduction: sugar cane is a giant plant of grain products. regarding the benefits of the use of medications with herbal origin, in the present study the impact of sugar cane extract on atherosclerosis and ldl-c and hdl-c in the serum of hypercholesterolemic rabbits was studied. materials and methods: 24 adult male new zealand rabbits race with an average weight of 2 kg were classified into fo...

the concentration of adiponectin, a hormone which is secreted from adipose tissue, is inversely correlated with body fat mass. this hormone has anti inflammatory and anti atherogenic properties. its concentration reduces in metabolic syndrome and cardiovascular diseases. this study reviews the evidence on the relationship between serum adiponectin concentration and lipid profile. in this study ...

We have recently reported that oxidized low density lipoprotein (ox-LDL) inhibits endothelium-dependent arterial relaxation through its increased lysophosphatidylcholine (LPC). In this study we examined whether high density lipoprotein (HDL) has any effect on the inhibition of endothelium-dependent relaxation by ox-LDL in isolated strips of rabbit thoracic aorta. Both low density lipoprotein (L...

BACKGROUND The purpose of this study was to assess the feasibility of infrared (IR) spectroscopy for the simultaneous quantification of serum LDL-cholesterol (LDL-C) and HDL-cholesterol (HDL-C) concentrations. METHODS Serum samples (n = 90) were obtained. Duplicate aliquots (5 microL) of the serum specimens were dried onto IR-transparent barium fluoride substrates, and transmission IR spectra...