The perception of sound in architectural spaces is influenced by two main factors: the properties of the space in which the sound is produced, and the properties of the source producing the sound. This research project uses computational modeling to study the effect of these properties on the binaural response in a virtual space. Two independent parameters were studied: the scattering coefficie...

Linear duration invariants (LDI) are important safety properties of real-time systems. They can be easily formulated in terms of a class of chop-free formulas in the Duration Calculus (DC). Compared to other temporal logics, the specification in DC is simpler, neater and more importantly easier to understand. However, directly model checking them is more difficult than model checking properties...

Here, we report a long-distance interaction (LDI) as a critical regulator of alternative splicing of Survival Motor Neuron 2 (SMN2) exon 7, skipping of which is linked to spinal muscular atrophy (SMA), a leading genetic disease of children and infants. We show that this LDI is linked to a unique intra-intronic structure that we term internal stem through LDI-1 (ISTL1). We used site-specific mut...

Control of parametric laser-plasma interactions (LPI) is essential to the success of inertial confinement fusion (ICF). Through a research collaboration with the Los Alamos National Laboratory (LANL), we have had the opportunity to participate in world-class laser-plasma experiments. The goal of these experiments was to gain a fundamental understanding of LPI by studying the interaction of a si...

article entitled 'Comparison of laser Doppler imaging, fi ngertip lacticemy test, and nailfold capillaroscopy for assess ment of digital microcirculation in systemic sclerosis' [2], which was published in a recent issue of Arthritis Research & Th erapy. Sulli and colleagues commented on our results regarding the lack of correlation between the laser Doppler imaging (LDI) technique and nailfold ...

Amidopyrene-conjugated compounds can be detected by label-assisted laser desorption/ionization mass spectrometry (LA-LDI MS) without matrixes. When actin, a cytoskeletal protein, was labeled with an excess amount of amidopyrene N-hydroxysuccinate (apy-OSu), eight apy-labeled actin peptides were predominantly detected by LA-LDI MS. Then actin was labeled with an amidopyrene NHS ester of the anti...

BACKGROUND Medical patients with limited English proficiency (LEP) frequently receive health care services of suboptimal quality. METHODS We explored whether clients served with staff interpreters (language-discordant, LDI) receive reproductive health care of lower quality than clients seen by a bilingual clinician (language concordant, LC). We conducted a medical record review of 1,589 repro...

This paper proposes a new hardware-assisted LDI Building algorithm with application to hybrid volume rendering. It works by creating Layered Depth Image (LDI) using OpenGL. Together with LDI, the scene can be rendered by intermixing segmented volume data and stored depth lists easily. The highlight of our algorithm is that it creates a z-sorting list simply by using depth and stencil buffer in ...

This paper presents the first field study of aimed movements in graphical user interfaces, designed to get better insight into pointing in the real (electronic) world and assess the validity of Fitts’ law in the wild. We unobtrusively collected kinematic data from 24 users over several months, and segmented it into a table of 2 million movements. We show that Fitts’ law is indeed robust for mod...