The anthelmintic properties and composition of an Italian traditional remedy based on a red algae mixture (RAE) was assessed using the egg hatch test (EHT). ability different dilutions \((1.0, 5.0, 50, or 100%)\) RAE determined compared with positive negative controls against gastrointestinal nematode (GIN) donkeys. experiment performed in triplicate. Data were analysed ANOVA Tukey test. In mix...

Chun-Shun Li, Xiao-Ming Li, Chuan-Ming Cui, and Bin-Gui Wang Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Nanhai Road 7, Qingdao 266071, P. R. China Reprint requests to Prof. Dr. Bin-Gui Wang. Fax: +86-532-82880645. E-mail: [email protected] Z. Naturforsch. 2010, 65b, 87 – 89; received October 10, 2009 One new sesquiterpenoid, aristolan...

Four new (1-4) and six previously reported (5-10) α-pyrone polyketides, along with benzoic acid, hydrocinnamic acid, and (E)-cinnamic acid, were isolated from the organic extract resulting from the cultivation of the algicolous strain Streptomyces ambofaciens BI0048, which in turn was isolated from the inner tissues of the red alga Laurencia glandulifera. The structure elucidation of the isolat...

Chromatographic fractionation of the CH₂Cl₂/MeOH extract of the Red Sea red alga Laurencia obtusa gave two new hexahydrofuro[3,2-b]furan-based C15-acetogenins, namely, isolaurenidificin (1) and bromlaurenidificin (2). The chemical structures were elucidated based on extensive analyses of their spectral data. Compounds 1 and 2 showed no toxicity (LC50 > 12 mM) using Artemia salina as test organi...

The enantioselective total syntheses of (-)(E)ybisabolene-8,9-epoxide, (+) (2S,6R)-2-bromo-13-chamigrene, and (+)-chamigrene, important intermediates in the biosynthesis of natural sesquiterpenoids isolated from algae of the genus Laurencia, are described. The compounds are synthesized with regio ñd stereocontrol by using simple forms of bridged intermediates. This represents a general strategy...