Introduction: The Papuan people have utilized the native herb Laportea decumana (Roxb.) Wedd for centuries to treat aches and pains L. is used by attaching leaves to the body area with illness. Methods: This study aimed test optimal composition of PEG 400 and 6000 in L.decumana  simplicia ointment formula produce a good ...

Metabolic study of bioactive compounds that undergo a dynamic and sequential process of metabolism is still a great challenge. Salidroside, one of the most active ingredients of Rhodiola crenulata, can be metabolized in different sites before being absorbed into the systemic blood stream. This study proposed an approach for describing the sequential biotransformation process of salidroside base...

The species diversity of ostracods in the floodplain of the Chi River basin, Mahasarakham Province, Northeast Thailand was examined in this study. Twenty-two samples were collected in the cool season (February 2010). Twenty-six species belonging to 18 genera were recorded, three of which are new to the Oriental region (Fabaeformiscandona subacuta (Yang, 1982), Ilyocypris monstrifica (Norman, 18...

Hemocyanin Channel, Planar Lipid Bilayer, Carbohydrates, D ivalent Cations, Protein Conformations The effects o f glucose and sucrose on the ionic conductance properties o f the channel formed by Megathura crenulata hemocyanin in planar lipid bilayers have been studied using membranes of different compositions. It was found that glucose at high concentrations strongly affects the time constants...

In the present study, two new phenolic compounds 1 and 11, a pair of lignan isomers 12 and 13 with their absolute configurations established for the first time, were isolated from the ethanol extract of the roots of Rhodiola crenulata, together with 13 known phenolic compounds, and their structures were elucidated via NMR, HRESIMS, UV, IR and CD analyses. All the isolated compounds were evaluat...

Immunization with a T-cell dependent antigen has been promoted as a reliable and sensitive tool for assessing the influence of putative immunotoxic exposures or agents on immune function. Keyhole limpet haemocyanin (KLH) is a very large, copper-containing protein molecule derived from the haemolymph of the inedible mollusc, Megathura crenulata. KLH is a highly immunogenic T-cell dependent antig...