Next-generation sequencing data pose a severe curse of dimensionality, complicating traditional "single marker-single trait" analysis. We propose a two-stage combined p-value method for pathway analysis. The first stage is at the gene level, where we integrate effects within a gene using the Sequence Kernel Association Test (SKAT). The second stage is at the pathway level, where we perform a co...

Department of Physics, Lancaster University, Lancaster, LA1 4YB, UK. Now at: Meteorological Service, Ministry of Agriculture, Natural Resources and Environment, 1418 Nicosia, Cyprus. Permanent address: Department of Physics, University of Florida, PO Box 118440, Gainesville, FL 32611, USA. Permanent address: Joint Low Temperature Laboratory, Institute of Physics ASCR, and Faculty of Mathematics...

This paper first discusses standards for developing Asian language corpora so as to facilitate international data exchange. Following this, we present two corpora of Asian languages developed at Lancaster University – the EMILLE Corpus, which contains 14 South Asian languages, and the Lancaster Corpus of Mandarin Chinese. Finally, we will demonstrate how to explore these corpora using Xara and ...

Christopher F. H. Nam, John A. D. Aston, Idris A. Eckley, Rebecca Killick Department of Statistics, University of Warwick, Coventry, CV4 7AL, UK Statistical Laboratory, DPMMS, University of Cambridge, Cambridge, CB3 0WB, UK Department of Mathematics and Statistics, University of Lancaster, Lancaster, LA1 4YF, UK {c.f.h.nam | j.a.d.aston }@warwick.ac.uk {i.eckley | r.killick }@lancaster.ac.uk Fe...

Steffen Zschaler1, Pablo Sánchez2, João Santos3, Mauricio Alférez3, Awais Rashid1, Lidia Fuentes2, Ana Moreira3, João Araújo3, Uirá Kulesza 1 Computing Department, Lancaster University, Lancaster, United Kingdom {zschaler, awais}@comp.lancs.ac.uk 2 Departamento de Lenguajes y Ciencias de la Computación, Universidad de Málaga, Malaga, Spain {pablo,lff}@lcc.uma.es 3 Computer Science Department, U...

A. Vagov, 2 H. Schomerus, and V. V. Zalipaev 4 Institut für Theoretische Physik III, Bayreuth Universität, Bayreuth 95440, Germany Department of Physics, Lancaster University, Lancaster LA1 4YB, United Kingdom Steklov Mathematical Institute, Fontanka 27, St.-Petersburg 191023, Russia 4 Department of Mathematical Sciences, University of Liverpool, Liverpool L69 7ZL, United Kingdom (Dated: July 9...

• you should observe the conventions of academic citation in a version of the following form: Bob Jessop, 'The Governance of Complexity and the Complexity of Governance: Preliminary Remarks on some Problems and Limits of Economic Guidance', published by the Department of Sociology, Lancaster University, Lancaster LA1 4YN, at http://www.comp.lancs.ac.uk/sociology/papers/Jessop-Governance-ofCompl...

* Department of Molecular & Cell Biology, Henry Wellcome Building, University of Leicester, Lancaster Road, Leicester, LE1 7RH, UK † Proteomics Facility, Protein and Nucleic Acid Chemistry Laboratory, Hodgkin Building, University of Leicester, Lancaster Road, Leicester, LE1 7RH, UK ‡ Human Physiology, College of Health, Massey University at Albany, North Shore, Auckland, 0630, NZ Corresponding ...

A kinetic model of radiating electrons A. Noble,1 D. A. Burton,2 J. Gratus,2 and D. A. Jaroszynski1 1SUPA and University of Strathclyde, Glasgow G4 0NG, United Kingdom 2Department of Physics, Lancaster University, Lancaster LA1 4YB, United Kingdom and The Cockcroft Institute of Accelerator Science and Technology, Daresbury Science and Innovation Campus, Daresbury, Warrington WA4 4AD, United Kin...

Anupam Mazumdar, Saleh Qutub, and Ken’ichi Saikawa Consortium for Fundamental Physics, Physics Department, Lancaster University, Lancaster LA1 4YB, United Kingdom Kapteyn Astronomical Institute, University of Groningen, 9700 AV Groningen, Netherlands Department of Astronomy, King Abdulaziz University, Jeddah 21589, Saudi Arabia Deutsches Elektronen-Synchrotron DESY, Notkestrasse 85, 22607 Hambu...