Importance A growing number of neurologic treatments rely on neural implants capable of delivering electrical and chemical stimulation to targeted regions of the central nervous system for extended periods. Objective To assess the potential of a novel class of multimodal neural implants, termed electronic dura mater or e-dura, to fulfill this need. Evidence Review Results from preclinical a...

OBJECTIVE To evaluate the periapical repair after root canal treatment in the teeth of dogs using CT and conventional radiography and to compare these findings with the gold standard microscopic evaluation. STUDY DESIGN The animals were divided into three groups according to endodontic treatment performed: Group 1, single-visit endodontic treatment in teeth without apical periodontitis; Group...

Background: Dura substitutes are commonly required to repair the dura mater during routine neurosurgical procedures. Biologic materials composed of xenogenic collagen represent the most prevalent dura substitute, yet often incite undesirable tissue responses that impair wound healing. New materials are therefore needed to overcome the shortcomings of existing products and facilitate effective a...

BACKGROUND The prosthetic dura is an essential element in the protection of the cranial parenchyma and prevention of cerebrospinal fluid leakage. Although prosthetic dura are widely used in neurosurgery, they occasionally provoke infection, which can be a major concern after neurosurgical treatment. However, removal of the prosthetic dura carries a risk of brain parenchyma injury and cerebrospi...

primary non-hodgkin’s lymphoma of the cranial vault is extremely rare. this case report presents a 42-year-old man with a painless subcutaneous scalp mass which extended intracranially associated with recent mild headache. initial computed tomography and magnetic resonance imaging revealed two lesions emanating from the skull. biopsy revealed a diagnosis of diffuse large b cell lymphoma (dlbcl)...

BACKGROUND Although reossification of large calvarial defects is possible in children, adults lack this tissue engineering capacity. In this study, the authors compared the differences in gene expression between juvenile and adult dura mater using a mouse cDNA microarray with 42,000 unique elements. METHODS Non-suture-associated parietal bone was harvested from 6-day-old and 60-day-old mice. ...

Introduction. Removal of non-brain tissues, particularly dura, is an important step in enabling accurate measurements of brain structures. Previous approaches (2,5,6) can lead to brain loss and/or leave residual dura (4), posing a problem for subsequent cortical thickness estimation. Brain loss cannot be reversed downstream in the segmentation pipeline. Inclusion of dura mater can cause overest...

Literature addressing the anatomic development of the dura and calvarium during childhood is limited. Nevertheless, histological features of a subdural neomembrane (NM), including its thickness and vascularity, developing in response to an acute subdural hematoma (SDH) have been compared to the dura of adults to estimate when an injury occurred. Therefore, we measured the morphometric growth of...