INTRODUCTION Butter oil, ghee and butter are theoretically low in lactose. All three products are high in milk fat; butter oil and ghee contain approximately 99.3% fat and butter around 80% fat. We report the lactose and galactose content of butter, ghee, and butter oil and assess their suitability in a low galactose diet. METHODS A total of 12 samples (butter oil n = 5, ghee n = 5, butter n ...

Thirty-eight infants and young children with gastroenteritis were investigated for lactose malabsorption. Each of them was given an oral lactose load of either 0.5 g/kg or 2 g/kg after which breath hydrogen excretion was measured, and each was observed to see if he had clinical symptoms of lactose intolerance. Only one patient, given 2 g/kg lactose, had clinical intolerance. His breath hydrogen...

Sugar analysis is a common industrial analytical requirement. It is particularly important in the analysis of food products such as milk. Though lactose is the main carbohydrate in milk (1) and was typically the only sugar of concern, recently interest has expanded in analyzing milk products with reduced lactose. The lactose in milk can be reduced by hydrolyzing lactose into two other sugars, g...

Adult‑type hypolactasia (lactase nonpersistence or lactase deficiency) is the most common enzyme deficiency leading to lactose intolerance and primary lactose malabsorption. Clinical presentation of the condition includes symptoms resulting from bacterial fermentation of undigested lactose in the colon, which gives rise to gas bloat, increased motility, and loose stools. Diagnosis of the diseas...

Lactose, a unique disaccharide, occurring exclusively in the mammalian milk plays an important role in nutrition. Most of the lactose that is manufactured on an industrial scale is produced from whey derived from the production of cheese, casein or paneer using crystallization and purification technologies. Lactose can be converted to various derivatives like lactitol, lactobionic acid, galacto...

Over the last decade, conical mill has emerged as a potential piece of equipment to use for continuous dry coating pharmaceutical powders. In this work, silicon dioxide was used guest particle on two excipients, fast flow lactose (FFL) and grade PH200 microcrystalline cellulose (MCC), by with modified screen that permitted batch mode operation. Samples were pre-processed in V-blender. SEM image...

The incidence of lactose malabsorption was investigated in 85 patients with ulcerative colitis and 71 patients with Crohn's disease by means of lactose tolerance tests and disaccharidase determinations in small intestinal mucosa. Eight patients with ulcerative colitis (9%) and four with Crohn's disease (6%) had lactose malabsorption. A control group displayed a similar incidence. It is conclude...

In 1935, Grant (1) successfully demonstrated the in vitro biosynthesis of lactose from glucose in slices of guinea pig mammary gland. Lactose was determined by a differential fermentation method. Under the conditions employed, sugar phosphates were not converted to lactose either in slices or minces of lactating gland. Recently this work was confirmed and extended by Malpress and Morrison (a), ...

BACKGROUND Lactose, as the primary osmotic component in milk, is the major determinant of milk volume. Glucose is the primary precursor of lactose. However, the effect of glucose on lactose synthesis in dairy cow mammary glands and the mechanism governing this process are poorly understood. RESULTS Here we showed that glucose has the ability to induce lactose synthesis in dairy cow mammary ep...

Escherichia coli lactose permease (LacY) transports sugar across the inner membrane of the bacterium using the proton motive force to accumulate sugar in the cytosol. We have probed lactose conduction across LacY using steered molecular dynamics, permitting us to follow molecular and energetic details of lactose interaction with the lumen of LacY during its permeation. Lactose induces a widenin...