Existing research indicates that different dimensions of the design of international institutions are interrelated. In particular, deep agreements have been shown to be more flexible. We make two contributions to this literature. On the one hand, we argue and empirically show that the positive relationship between depth and flexibility holds for preferential trade agreements (PTAs). On the othe...

BACKGROUND Data on the cocaine market appear inconsistent, as they tend to show declining prices vis-a-vis steady or increasing demand and a declining supply. This paper proposes an explanation for this trend by providing evidence of an under-estimation of the supply of cocaine. METHODS We propose a conservative estimate of cocaine production in Colombia for 2008, using data based on all repo...

In this paper we explore what predicts data quality and participation by human subjects in an online, games-for-science community. The advent of games for science, citizen science, and online laboratories represent a new world of possibilities for conducting scientific research with human subjects. However, many questions remain about the quality of participation across individual games. In thi...

We present the first standardized HLA peptidomics dataset generated by the immunopeptidomics community. The dataset is composed of native HLA class I peptides as well as synthetic HLA class II peptides that were acquired in data-dependent acquisition mode using multiple types of mass spectrometers. All laboratories used the spiked-in landmark iRT peptides for retention time normalization and da...

The Earth's islands harbor a distinct, yet highly threatened, biological and cultural diversity that has been shaped by geographic isolation and unique environments. Island systems are key natural laboratories for testing theory in ecology and evolution. However, despite their potential usefulness for research, a quantitative description of island environments and an environmental classificatio...

Across independent cancer genomes it has been observed that some sites have been recurrently hit by single nucleotide variants (SNVs). Such recurrently hit sites might be either (i) drivers of cancer that are postively selected during oncogenesis, (ii) due to mutation rate variation, or (iii) due to sequencing and assembly errors. We have investigated the cause of recurrently hit sites in a dat...

As microarray technologies become routinely applied in genome laboratories for studying gene expression, it is not uncommon that experiments on identical or similar sets of genes are conducted by multiple laboratories for various functional studies of these genes. Much of such data are often available to researchers for their data analysis, either through collaborators or from online gene expre...