Spontaneous preterm labor is an important complication in perinatology characterized by early onset myometrium contractions leading to labor at preterm. However, the exact mechanism that maintain uterine quiescence and promote increased uterine contractility during labor were incompletely defined. MicroRNAs is a class of short non-coding RNAs that regulate gene expression at the post-transcript...

Labor and Delivery is a complex clinical service requiring the support of highly trained healthcare professionals from Obstetrics, Anesthesiology, and Neonatology and the access to a finite set of valuable resources. In the United States, the rate of cesarean sections on labor floors is approximately twice as high as considered appropriate for patient care. We analyze one month of data from a B...

Despite popular belief, exercise while pregnant does not initiate labor, or preterm labor. Exercise is associated with delivering closer to the due date. Further, maternal exercise is associated with either no change, or shorter labor and delivery overall. Women who exercised had less complications during labor and delivery than those who did not exercise. More importantly, measures of the fetu...

In this study, delivery care in the city of Londrina, State of Paraná, was investigated under the focus of health professionals' decisions to prescribe procedures such as fasting, enema and trichotomy. The theoretical referential was historical and dialectical materialism. The data survey was carried out in 2000 in five institutions and included individual interviews with ten obstetricians, eig...

abstract background: prolonged labor can lead to maternal and neonatal complications. the purpose of this study was to investigate the effect of oral propranolol plus oxytocin versus oxytocin only on the process and outcome of labor. materials and methods: in a randomized, double-blind, controlled trial performed in ilam mustafa hospital, a total of 146 nulliparous pregnant women at gestational...

abstract considering that vaginal delivery is a painful process, the present study investigated the effects of citrus aurantium on the severity of first-stage labor pain in primiparous women. this study was a randomized clinical trial conducted with 126 eligible primiparous patients. the pain severity of patients was measured at the time of enrolling in the study. in the intervention group, (ar...

The objective of this study was to identify possible changes in mRNA and protein expression of high-mobility group box protein 1 (HMGB1) and its suggested receptors - receptor for advanced glycation end-products (RAGE) and Toll-like receptor 2 (TLR2) and TLR4 - in human cervix during pregnancy, term and preterm labor. Cervical biopsies were taken from 58 women: 20 at preterm labor, 24 at term l...