AIMS To describe ticlopidine related microscopic colitis and to assess the occurrence of apoptosis in the colon epithelium. METHODS A series of colorectal biopsy samples from nine patients with ticlopidine related chronic diarrhoea were analysed. Biopsies were also taken from five of these patients between two and four months after ticlopidine withdrawal. The number of apoptotic cells in the ...

Thymidine is a specific precursor of deoxyribonucleic acid (DNA) and is utilized for chromosomal replication by the nuclei of cells when they double their DNA content in interphase before cell division (Reichard and Estborn, 1951; Friedkin, Tilson, and Roberts, 1956; Gall and Johnson, 1960; Mirsky and Osawa, 1961). Autoradiography after the administration of thymidine labelled with tritium (3H-...

In the paper we present a method to estimate relative depth between objects in scenes of video sequences. The information for the estimation of the relative depth is obtained from the overlapping produced between objects when there is relative motion as well as from motion coherence between neighbouring regions. A relaxation labelling algorithm is used to solve conflicts and assign every region...

PURPOSE The aim of study was to test by immunohistochemical (IHC) staining whether carbonic anhydrase (CA) 9 and 12 have an effect on sentinel lymph node (SLN) metastasis in early breast cancer and to find clinicopathologic factors associated with SLN metastasis. MATERIALS AND METHODS Between June 2003 and June 2011, medical records of 470 patients diagnosed with breast cancer with pT1-2, pN0...

The aim of this study was to examine the effect of long-term treatment with glucocorticoids on the uterine response to oestradiol. Ovariectomized rats were treated with crystal triamcinolone acetonide (0.1 mg/100 g, i.m.) or saline (0.1 ml/100 g i.m.) for 29 days. Over this period five injections were administered, one per week. On the second day after the last triamcinolone injection, rats wer...

AIM To investigate whether the expression of apoptosis and cell proliferation related proteins is related to the macroscopic form of colorectal neoplasia. METHODS The extent of apoptosis, using the 3' end DNA labelling method, and the immunohistochemical expression of cell proliferation (Ki-67) and apoptosis related proteins (Bcl-2, Bak, and p53) were investigated in 64 colorectal adenomas an...