Background: Dendritic cells (DCs) are professional antigen presenting cells (APCs), and there is considerable interest in their application as a cellular adjuvant for cancer immunotherapy.  Previous studies indirectly demonstrated that DCs were able to take up tumor lysate (crude soluble tumor antigens) and also cross-present tumor associated antigens (TAA) which elicits anti-tumor immune respo...

background: to date, several imaging techniques to track stem cells are used such as positron emission tomography (pet), single photon emission computed tomography (spect), bioluminescence imaging (bli), fluorescence imaging, ct scan and magnetic resonance imaging (mri). although, overall sensitivity of mri compared to spect and bioluminescence techniques are lower, but due to high spatial reso...

  Background & Objectives: Antisense peptide nucleic acids (PNA) that target growth essential genes show potent bactericidal properties without cell lysis. We considered the possibility that whether PNA treatment influence the bacteria total nucleic acids content and apply approach to develop a new delivery system to Dendritic cells (DCs). DCs are the most potent antigen presenting cells in th...

two groups of antibodies against mouse resident alveolar and peritoneal macrophages have been raised individually in rabbits by immunization with whole cell suspensions of lavaged alveolar and peritoneal macrophages. the whole antisera reacted positively with neutrophils and lymphocytes. however, upon extensive absorptions with these cells the activity became restricted to macrophages. the immu...

many cellular damages either in normal or cancerous tissues are the outcome of molecular events affected by ionizing radiation. t‑cells are the most important among immune system agents and are used for biological radiation dose measurement in recommended standard methods. the herbs with immune modulating properties may be useful to reduce the risk of the damages and subsequently the diseases. ...

background & objectives: antisense peptide nucleic acids (pna) that target growth essential genes show potent bactericidal properties without cell lysis. we considered the possibility that whether pna treatment influence the bacteria total nucleic acids content and apply approach to develop a new delivery system to dendritic cells (dcs). dcs are the most potent antigen presenting cells in t...

Introduction: The radioimmunoscintigraphy (RIS) has found widespread clinical applications in  tumor  diagnosis.  Human  epithelial  mucin,  MUC1,  is  commonly  over  expressed  in  adenocarcinoma including 80% of breast cancers and represents a useful target for RIS. The PR81  is  a  new  murine  anti-MUC1  monoclonal  antibody  that  was  found  to  react  with  the  membrane  extracts of se...