Aminotransferases (ATs) interacting with L-alanine are the least studied bacterial ATs. Whereas AlaT converts pyruvate to L-alanine in a glutamate-dependent reaction, AvtA is able to convert pyruvate to L-alanine in an L-valine-dependent manner. We show here that the wild type of Corynebacterium glutamicum with a deletion of either of the corresponding genes does not exhibit an explicit growth ...

This work focuses on the experimental measurement and modeling of solid–liquid equilibria containing continuous binary solid solutions crystallized from solvent mixtures for usage in antisolvent crystallization. The newly constructed quaternary phase diagrams l-valine/l-leucine water/2-propanol water/acetone systems are analyzed compared to those water/ethanol mixtures. Experimental data sets d...

the present study was carried out to examine the effect of supplemental dietary valine in the starter diet of broilers (0-15 d of age) on performance, antibodyresponse to newcastle disease virus vaccination and bone mineralization. the experiment was conducted using 300 ross 308 male broilers. one-day-old chicks were randomly allotted to 3 groups; each group consisted of 5 replicate pens with 2...

Since the discovery of CNT by Iijima, Nature 354, 56 (1991), CNT's have surged to the forefront as a versatile nanostructured material in nanoelectronic applications. Polypeptides nanotubular structures with tunable properties offer a challenging alternative to CNT. Earlier experimental studies on L-Alanyl-L-Valine (AV) and L-Valyl-L-Alanine (VA) have demonstrated their potential as novel porou...

(2S,3R)-3-Amino-2-hydroxyoctanoic acid was synthesized by Curtius rearrangement of an azide derivative of (S)-malic acid. Total syntheses of valinoctin A and its analogues were achieved by a coupling of (2S, 3R)-3-amino-2-hydroxyoctanoic acid moiety with L-valine or several other amino acids moieties. 2S configuration of 3-amino-2-hydroxyoctanoic acid moiety was found to be important for the in...

Peptide transporters (PEPT1 and PEPT2) in epithelia play an important role in the absorption of small peptides and peptide-like drugs. Recently, it was demonstrated that various nonpeptidic compounds can be transported by these transporters. In the present study, we focused on the L-amino acid ester compounds and examined the mechanisms of their interaction with rat PEPTs (rPEPTs) using stable ...

Pea (Pisum sativum L. cv Alaska) root tips were excised and cultured aseptically in White's medium. Cultures were treated immediately or after a 24 hour equilibration time with 28 nanomolar chlorsulfuron plus isoleucine and valine (each 0.1 millimolar), isoleucine and valine, or untreated. The percentage of mitotic figures in untreated control roots sampled immediately after excision showed a t...