The coexistence of both kidney and colon primary malignancies is a rare condition. We report the case of a 75-year-old woman who presented with bilateral pulmonary nodules at chest X-ray and stratigraphy. Total-body CT scan showed multiple, apparently metastatic, bilateral pulmonary lesions, a diffusely dysomogeneous neoformation in the lower pole of the right kidney and a gross neoformation in...

Neoplastic lesions of the kidney and certain other organs are sometimes associated with increased erythropoietin and/or erythrocytosis in man and experimental animals. It seems likely that measurement of erythropoietin, although not specific, could be helpful in detecting renal neoplasms and in following the progress of treated tumors of the kidney and certain other organs. Increasing the sensi...

INTRODUCTION Nerve sheath tumours of the kidney are particularly rare and, in the few reported cases, are all situated in the hilar region. CASE PRESENTATION We describe the case of a tumour presenting towards the lateral border of the ventral aspect of the mid-zone of the kidney. This was a spindle cell lesion in which the cells strongly and diffusely expressed cytokeratins, but were negativ...

INTRODUCTION Primitive neuroectodermal tumors (PNETs) occur predominantly in childhood preferentially in the soft tissues of the lower extremity and the paraspinal region. We present here a rare case of a PNET of the kidney in an adult. CASE PRESENTATION A tumor adjacent to the right kidney was detected by ultrasound coincidentally at a routine check-up in a 46-year-old woman with irritable b...

Renal cancer accounts for 3% of malignant neoplasms in adults. In 2008, more than 54,000 cases of kidney cancer were diagnosed, and more than 13,000 deaths occurred in the United States. In 2006, the number of deaths from renal cancer was 26,400 in the European Union and more than 100,000 worldwide. The cost of care for kidney cancer in the United States alone was more than $4.4 billion in 2004...

Introduction. At least 3% of all cancer cases are associated with hereditary changes in genes predisposing to malignant neoplasms. In addition the widely known BRCA1,2 genes, other involved equally DNA repair system and maintenance genome integrity, such as PALB2, CHEK2, being introduced into routine diagnosis. this review we present current information from recent studies on structure function...

The standard therapy for thyroid cancer is total or near total thyroidectomy, followed by the administration of radioactive iodine for remnant ablation or residual disease. Patients with radioiodine therapy are predisposed to second malignant neoplasms in organs such as central nervous system (CNS), breast, prostate, kidney, bone marrow, salivary gland, and digestive tract. Exposure to carcinog...

Abstract Background and Aims Myeloproliferative neoplasms (MPN) are chronic blood disorders defined by an overproduction of clonal, differentiated hematopoietic cells. A high prevalence kidney disease (CKD) is described in patients with MPN. The glomerular histological pattern MPN-related disease, glomerulopathy (MPN-RG), may not account for the entirety CKD risk this population, as it appears ...

BACKGROUND Excess risks of several second neoplasms following breast cancer have been reported. However, these risks have still to be quantified. PATIENTS AND METHODS We considered 9,729 breast cancer patients registered by the Swiss Cancer Registries of Vaud and Neuchâtel (covering about 786,000 inhabitants) and followed up from 1974 to 1998. RESULTS Overall, 443 second primary neoplasms (...

Prostate, bladder and kidney cancers remain the most common urological malignancies worldwide, and the prevention and treatment of these diseases pose a challenge to clinicians. In recent decades, many studies have been conducted to assess the association between supplementation with selected vitamins and elements and urinary tract tumour initiation and development. Here, we review the relation...