Melissa officinalis L. (Labiatae) traditionally used in treating neurological disorders has also been identified as a memory-enhancing herb. The extract of M. officinalis has a cholinergic property. The role of basal forebrain cholinergic neurons, the neurons that are destroyed in Alzheimer's disease (AD), in learning and memory, is also well known. The aim of this study is to investigate the r...

BACKGROUND Extracts and essential oils of medicinal plants are increasingly of interest as novel drugs for antiherpetic agents, since the herpes simplex virus (HSV) might develop resistance to commonly used antiviral drugs. METHODS An aqueous extract of Melissa officinalis as well as phenolic extract compounds, i.e. caffeic acid, p-coumaric acid and rosmarinic acid were examined for their ant...

The methanolic extracts, infusions, decoctions and hydrosols of six plants were investigated for their total phenolic contents, antioxidant and antimicrobial activities: Mentha piperita (Peppermint), Thymus vulgaris (thyme), Melissa officinalis (lemon balm), Ocimum basilicum (basil), Rosmarinus officinalis (rosemary) and Salvia officinalis (sage) (Lamiaceae). Total phenolic contents were determ...

introduction: unsaturated fatty acids , one of the most important components of biological membranes , are very sensitive to oxidation processes. damage to cells and tissues by oxidation of these kinds of acids is one of the most important contributing  factors in many diseases, such as, atherosclerosis, rheumatoid arthritis and cancer. there are some available antioxidant synthetic compounds i...

Extensive research suggests that a number of plant-derived chemicals and traditional Oriental herbal remedies possess cognition-enhancing properties. Widely used current treatments for dementia include extracts of Ginkgo biloba and several alkaloidal, and therefore toxic, plant-derived cholinergic agents. Several non-toxic, European herbal species have pan-cultural traditions as treatments for ...

alzheimer’s disease (ad) is a neurodegenerative disease that was characterized with deposit of beta amyloid (aβ) aggregate in senile plaque. oxidative damage to neurons and loss of cholinergic neurons in forebrain region are observed in this disease. melissa officinalis is a medicinal plant from lamiaceae family, used traditionally in the treatment of cognitive disorders. it has cholinomimetic ...