Department of Botany & Microbiology, Gurukul Kangri University Haridwar 249404, Uttarakhand, India ABSTRACT: Lipstatin, a new and very potent inhibitor of pancreatic lipase, was isolated from the Streptomyces toxytricini. Lipstatin contain a beta lactone structure that probably account for the irreversible lipase inhibition. As per the biosynthetic pathway the role of linoleic acid, palmitic ac...

Fatty acid binding protein was purified from renal medulla, and its binding activity and fatty acid composition were determined in spontaneously hypertensive stroke-prone rats (SHRSP). Wistar-Kyoto rats (WKY) were used as controls. Fatty acid binding activity was higher in 5-week-old prehypertensive SHRSP than in control WKY (0.155 +/- 0.006 vs 0.030 +/- 0.001 mol palmitic acid/mol protein). Ho...

A method for determination of palmitic acid in edible oils by the near-infrared spectroscopy was addressed in this paper. 56 samples were collected in the experiment. In terms of concentration content gradient method, 44 samples were selected for modeling set and 12 for testing set. This paper described the utilization of PLS for establishing a quantitative analysis model for predicting the con...

Methylated fatty acid (FA) compounds in the heartwood and bark of some softwood species, specifically Pinus sylvestris, Abies alba, Picea abies, and Larix decidua, grown in the Czech Republic were evaluated. Strong H2SO4 was used for methylation of the lipids. The highest content of lipid was found in P. abies bark (40.132 mg/g o.d. sample), and the lowest content was in A. alba wood (11.027 mg...

Specifically 14C-labeled palmitic acids were perfused through livers and incubated with slices of kidneys from rats in diabetic ketosis. The distribution of 14C in the hydroxybutyric acid formed was determined. In liver, the ratio of incorporation of 14C from [13-14C]palmitic acid into carbon 1 to carbon 3 of the hydroxybutyric acid was the same as the ratio in carbon 2 to carbon 4 from [6-14C]...

abstract this experiment was conducted to study the effect of south-west climatic conditions on quantitative and qualitative of fatty acids in dog rose (rosa canina l.) seeds collected from five regions including: semirom (isfahan province), kiar and gerdbishe (charmahal and bakhtiari province), yasuj and meymand (kohgiluye and boyer ahmad province). oil was extracted using soxhlet apparatus; t...

In metabolic syndrome, a systemic deregulation of the insulin pathway leads to a combined deregulation of insulin-regulated metabolism and cardiovascular functions. Free fatty acids (FFAs), which are increased in metabolic syndrome, inhibit insulin signaling and induce metabolic insulin resistance. This study was designed to examine FFAs' effects on vascular insulin signaling and endothelial ni...

Abdominal obesity is a key contributor of metabolic disease. Recent trials suggest that dietary fat quality affects abdominal fat content, where palmitic acid and linoleic acid influence abdominal obesity differently, while effects of n-3 polyunsaturated fatty acids are less studied. Also, fatty acid desaturation may be altered in abdominal obesity. We aimed to investigate cross-sectional assoc...

The mechanism by which palmitic and oleic acids modify calcium sequestration by sarcoplasmic reticulum vesicles was investigated by examining the effects of these fatty acids on calcium -dependent ATPase activity, on the phosphoenzyme intermediates found during calcium sequestration reactions, and on passive membrane permeability to calcium. The calcium sequestered in the presence of these fatt...