The purification and some of the properties of a flavoprotein component of a-ketoglutaric dehydrogenase complex have been described in a previous communication (1). In several of its properties, this flavoprotein shows a remarkable resemblance to the flavoprotein first isolated by Straub (2) and later studied by Savage (3). They have the same prosthetic group (flavin adenine dinucleotide) and a...

AIM The purpose of this research was to use metabolomics to investigate the cystic phenotype in the Lewis polycystic kidney rat. METHODS Spot urine samples were collected from four male Lewis control and five male Lewis polycystic kidney rats aged 5 weeks, before kidney function was significantly impaired. Metabolites were extracted from urine and analysed using gas chromatography-mass spectr...

Mycobacterium Zepraemurium multiplies in a cell-free liquid medium, referred to as NC-5, which is enriched Kirchner medium plus goat serum, a-ketoglutaric acid, cytochrome c, haemin, and L-cysteine. At 30 "C, the bacilli gradually elongated before multiplying 100to Iooo-fold. The maximum number of bacilli is reached after 8 weeks' incubation. The generation time of Mycobacterium lepraemurium is...

The Medical Examination of Hiroshima Patients with Radiation Cataracts: Paul G. Fillmore_ 322 Histochemical Demonstration of Protein-bound Sulfhydryl Groups: Russell J. Barrnett and Arnold M. Seligman ......... 323 Role of Coenzyme A and DPN in the Oxidation of a-Ketoglutaric Acid: D. R. Sanadi and J. W. Littlefield ..._............. 327 Direct Determination of Maximal Daily Metabolism of Alcoh...