Latar Belakang: Sepsis merupakan suatu kelainan sistemik akibat interaksi antara sistem imun dengan agen infeksi. Pada beberapa kasus, sepsis dapat berkembang menjadi syok septik dan kematian. Pasien kontaminasi bakteri yang terus berlangsung, resusitasi mungkin tidak berhasil sampai dilakukannya pengendalian sumber infeksi.Kasus: Seorang laki-laki 47 tahun diabetes telah terintubasi dalam pera...

INTRODUCTION Alcohol consumption is frequently associated with gastric mucosal lesions. The purpose of this study was to determine the effect of Coenzyme-Q10 (CoQ10) supplementation on the ethanol-induced gastric mucosal damage in a rat model. MATERIAL AND METHOD Sixty-four female wistar albino rats were randomly divided into 8 groups (n = 8). Studies were performed in ethanol induced gastric...

1. Horvath G. Szikszay M, Dobos I, Benedek G. Intrathecally applied α2-adrenoceptor agonist (hydrophil ST-91) effects on motor functions in rats. Second Congress of the Hungarian Neuroscience Society, Szeged, 26-28 January 1995. Neurobiology 3; 69, 1995. 2. Klimscha W, Horvath G, Szikszay M, Dobos I, Benedek G, Antinociceptive effects of the S(+) and racemic ketamnine isomers in acute pain test...

In 20 New Zealand rabbits (two groups of 10 rabbits each), hind limb circumference and anterior compartment pressure were measured following ketamin anaesthesia (time zero). During the same anaesthesia, closed transverse proximal tibial shaft fractures were created in both groups. Twenty-four hours after the fractures, during a second anaesthesia, limb circumference and compartment pressure wer...

A total of six adult animals were used for the study. Following anaesthesia via intraperitoneal injection of a mixture of ketamin and bombazine in ratio 2:1, thoracotomy was performed to exteriorize the heart for intracardial perfusion. The perfusion canular was inserted into the left ventricle and animal perfused sequentially with normal saline and 10% formal saline. Following perfusion, crani...

Ulcerative colitis is an inflammatory bowel disease (IBD) characterized by recurrent episodes of colonic inflammation and tissue degeneration in human or animal models. The contractile force generated by the smooth muscle is significantly attenuated, resulting in altered motility leading to diarrhea or constipation in IBD. The aim of this study is to clarify the altered contractility of circula...