Studies on animal models of epilepsy and cerebellar ataxia, e.g., stargazer mice (stg) have identified changes in the GABAergic properties of neurones associated with the affected brain loci. Whether these changes contribute to or constitute homeostatic adaptations to a state of altered neuronal excitability is as yet unknown. Using cultured cerebellar granule neurones from control [+/+; alpha-...

A functional analysis of AMPA and kainate receptors (AMPARs and KARs) in the lateral superior olive (LSO), a major nucleus in the auditory brainstem, has not been performed so far, to our knowledge. Here we investigated the presence and characteristics of such receptors in the rat LSO by means of whole-cell patch-clamp recordings in combination with pharmacology. Current responses evoked by 200...

Gündelik yaşamla ilgili her konunun klasik Türk şiirinde bir yansıması, farklı formlarla da olsa karşılığı bulunmaktadır. Her edebi gelenek gibi şairleri de toplum ve hayatıyla durumlardan kendilerine malzeme çıkarmışlardır. Mevsimler mevsimlere dair anlatımlar şiirin birçok formunda kullanılmıştır. Özellikle kaside nazım biçiminin nesib teşbip adı verilen giriş kısımlarında yer alan mevsimlerl...

heat stress is well recognized among the hazardous physical agents that might be present during work. this study aims to compare wbgt index at acclimated and unacclimated people to permissible threshold limit value and study the differences between physiological parameters at them. twenty one healthy men were participated in the study. all of the subjects were monitored in two different weather...

The Tso Kar lake basin in Ladakh, northwestern Himalayas (33 180N, 78 E, 4527 m a.s.l.) is located close to the modern boundary of effective moisture transport from the Indian summer monsoon. In order to reconstruct the possible monsoonal impact on the hydrology of the lake basin during the last 15 kyr, we studied the geomorphology of the basin and combined the results with multi-proxy records ...