Background & Objective: Soft tissue sarcomas (STS) constitute an uncommon and heterogeneous group of tumors of mesenchymal origin and various cytogenetic abnormalities ranging from distinct genomic rearrangements, such as chromosomal translocations and amplifications, to more intricate rearrangements involving multiple chromosomes. Fluorescence in situ...

Clear cell sarcomas are rare tumours accounting for less than 1% of all soft tissue tumours. They aggressive lesions with extremely poor prognosis. The clinical diagnosis this tumour is challenging, requiring histopathologic examination definite characterization. treatment protocol not well-established, most studies showing no clear cut role chemoradiation. This a case sarcoma in 57-year-old ma...

primary kaposi sarcoma of penis is very rare. we will introduce a 47 years old male patient referred to our clinic from dermatology service, in this report. the patient suffered from itchy penile papules around coronal region. the lab tests had revealed a negative serology of hiv but tissue pcr was positive for human herpesvirus-8 (hhv8).  histological findings were compatible with kaposi sarco...

Abstract Follicular dendritic cell (FDC) sarcoma, a rare tumor of FDCs, poses diagnostic challenge due to its myriad morphologic and architectural patterns. We present unique case extra-nodal FDC sarcoma occurring in 28-year-old gentleman who presented with multiple pelvic, peritoneal retroperitoneal soft tissue, axial skeletal lesions. The was composed islands trabeculae epithelioid cells inte...

testicular chloroma is an unusual form of extramedullary acute myeloid leukemia. we present a rare case that after chemotherapy relapsed with the appearance of metachronous testicular chloroma and we suggest prophylactic radiotherapy.

treatment with intensification of chemotherapy using alkylating agents and topoisomerase ii inhibitors and radiotherapy has improved the outcome of patients with solid tumors such as ewing’s sarcoma. however, there are several reports of secondary malignancy following treatment of these tumors. in this article, we describe a 12 years old girl with all who had ewing’s sarcoma when she was 8 year...

multiple primary tumors in a single patient are relatively rare when four or more distinct lesions are considered. herein, we report a case of woman with four different primary tumors: meningioma, renal angiomyolipoma, spinal ependymoma and high-grade soft tissue sarcoma. there was no family history and hereditary syndrome. the genetic analysis was completely normal. to best of our knowledge, t...

ewing's sarcoma (es) is a highly malignant neoplasm of childhood and adolescence seen commonly in both axial and appendicular skeleton but uncommonly in acral region. ewing’s tumor in the hand is extraordinarily rare. radiological features are variable and can mimic other common lesions. we present a case of 13 year old female, with complaints of pain and swelling in right hand, which on x-ray ...

Uterine sarcoma is a rare tumor of mesodermal origin, accounting for 2-6% of uterine malignancies. Leiomyosarcoma (LMS) has been reported in only 1% of all uterine malignancies and is regarded as the most common primary uterine sarcoma. Herein, we present a case of LMS with unusual macroscopic features. The patient was a 61-year-old woman with LMS, which consisted of a large cystic mass (88×136...