patients and methods in the present cross-sectional study, 109 patients with established hiv infection, who visited a governmental and referral center for hiv screening in tehran (tehran west health center (twhc)) between may 2014 and july 2015 were enrolled according to the convenience sample strategy. after peripheral blood collection, isolation of plasma and peripheral blood mononuclear cell...

EZH2 is a component of the epigenetic regulator PRC2 that suppresses gene expression. Elevated expression of EZH2 is common in human cancers and is associated with tumor progression and poor prognosis. In this study, we show that EZH2 elevation is associated with epigenetic modifications of Kaposi sarcoma-associated herpesvirus (KSHV), an oncogenic virus that promotes the development of Kaposi ...

Kaposi sarcoma herpesvirus (KSHV) induces transcriptional reprogramming of endothelial cells. In particular, KSHV-infected lymphatic endothelial cells (LECs) show an up-regulation of genes associated with blood vessel endothelial cells (BECs). Consequently, KSHV-infected tumor cells in Kaposi sarcoma are poorly differentiated endothelial cells, expressing markers of both LECs and BECs. MicroRNA...

Introduction Kaposi sarcoma is an angioproliferative disorder that requires infection with human herpesvirus 8 (HHV-8) for its development. The majority of cases are associated with HIV infection or other immunocompromising conditions. Thymomas are occasionally associated to cytopenia, which may alter the patients' immune responses. Methods Case report using clinical records. Results Case r...

Patients with human immunodeficiency virus infection are known to have increased risk of various neoplasms, including Kaposi sarcoma, which classically involves the skin and mucosal locations. The anaplastic variant of Kaposi sarcoma is rare and poorly documented in the literature. It is characterised clinically by a more aggressive behaviour and increased metastatic potential, and histological...

Kaposi sarcoma is a tumor consisting of Kaposi sarcoma herpesvirus (KSHV)-infected tumor cells that express endothelial cell (EC) markers and viral genes like v-cyclin, vFLIP, and LANA. Despite a strong link between KSHV infection and certain neoplasms, de novo virus infection of human primary cells does not readily lead to cellular transformation. We have studied the consequences of expression...

A 47 year old HIV positive male presented with haematemesis and epigastric pain. A gastrectomy was performed for intractable bleeding. The cause of the haematemesis proved to be a Kaposi sarcoma of the stomach which had resulted in mucosal ulceration. Several other smaller foci of Kaposi sarcoma were also present. Coexistent with the Kaposi sarcoma was a dense lymphoid infiltrate with lymphoid ...

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Liluashvili S, Pataraia Galdava G, Ghibradze T. Kaposi sarcoma in a kidney transplant recipient. Dermatology Review/Przegl?d Dermatologiczny. 2022;109(6):460-463. doi:10.5114/dr.2022.126605. APA Liluashvili, S., Pataraia, Galdava, G., & Ghibradze, (2022). Dermatologiczny, 109(6), 460-463. https://doi.org/10.5114/d...

conclusion there was no association between hhv-8 and mf or lpp in iranian population. this is in accordance with most of the reports from different countries. results the investigated samples consisted of 13 patient with mf, 10 patients with lpp, and 23 patients with chronic dermatitis; the diagnosis of these skin conditions were confirmed histopathologically. the rt-pcr could not detect hhv-8...

background and objectives:  the molecular genetic of the human herpes virus 8 (hhv8) has now been characterized the pathogenesis of kaposi sarcoma (ks). this study attempted to determine the rate of hhu-8 infection in ks in an iraniann cross sectional study. method & material: in this cross-sectional study, we used paraffin-embedded specimens of 54 clinically well-characterized kaposi sarco...