نتایج جستجو برای: kai1
تعداد نتایج: 194 فیلتر نتایج به سال:
Transmembrane 4 superfamily (TM4SF) is a recently described gene family, and TM4SF members are known to play roles in the signal transduction pathways and to regulate cell activation, development, proliferation, and motility. MRP-1/CD9, KAI1/CD82, and ME491/CD63, members of the TM4SF, have been reported to suppress tumor progression or metastasis. Previously, we showed that MRP-1/CD9 suppressed...
Reduced Tyk2 gene expression in b-cells due to natural mutation determines susceptibility to virus-induced diabetes Kenichi Izumi1,2,3,*, Keiichiro Mine1,*, Yoshitaka Inoue1, Miho Teshima1, Shuichiro Ogawa1, Yuji Kai1, Toshinobu Kurafuji1, Kanako Hirakawa1, Daiki Miyakawa1, Haruka Ikeda1, Akari Inada4, Manami Hara5, Hisakata Yamada6, Koichi Akashi2, Yoshiyuki Niho2, Keisuke Ina7, Takashi Kobaya...
Nerve growth factor (NGF) is expressed in the prostate, where it appears to be involved in the control of epithelial cell growth and differentiation. NGF production is decreased in prostate tumors. However, the role of this neurotrophin in the control of proliferation and progression of prostate cancers is still a matter of investigation. Prostate adenocarcinomas are telomerase-positive tumors....
Lichens produce various unique chemicals that can be used for pharmaceutical purposes. To screen for novel lichen secondary metabolites showing inhibitory activity against lung cancer cell motility, we tested acetone extracts of 13 lichen samples collected in Chile. Physciosporin, isolated from Pseudocyphellaria coriacea (Hook f. & Taylor) D.J. Galloway & P. James, was identified as an effectiv...
Interleukin-6, a multifunctional cytokine, contributes to tumor cell proliferation and differentiation. However, the biological mechanisms that are affected by the expression of interleukin-6 in bladder cancer cells remain unclear. We evaluated the effects of interleukin-6 expression in human bladder carcinoma cells in vitro and in vivo. The results of interleukin-6-knockdown experiments in T24...
We are very pleased to hear of the molecular abnormalities in two new pancreatoblastomas of Kerr et al. In our recent study of nine pancreatoblastomas, allelic loss on chromosome 11p15.5 was present in 6 of 7 informative cases (86%), and mutations in the APC/ -catenin pathway in 6 of 9 cases (67%). These findings underscore the clinical association between pancreatoblastoma formation and Beckwi...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید