Telomerase is a ribonucleoprotein enzyme that uses its internal RNA moiety as a template for synthesis of telomeric repeats at chromosome ends. Here we report the purification of'telomerase from Euplotes aediculatus by affinity chromatography with antisense 2'-O-methyl oligonucleotides, a method that was developed for small nuclear ribonucleoprotein particles (snRNPs). Elution of bound ribonucl...

Eco -friendly architectural principles are being incorporated into more buildings every day in the world but they are still out of reach of many people due to lack of knowledge and awareness. Nevertheless, many traditional societies learned to build collaborating with nature, basing their buildings on an intuitive knowledge of the environment and climate, constructing buildings at a very low co...

This paper examines the effects of negative priming and time pressure on creative problem solving, as measured by originality and practicality. In terms of negative priming, this paper builds on the work of Smith (1995, 2003). A negative prime is an example solution to a task that incorporates undesirable features, and is given to participants before they begin the task. In particular, attentio...

Crime maps have only recently begun to emerge as a significant tool in crime and justice. Until a decade ago, few criminal justice agencies had any capability for creating crime maps, and few investigators had the resources or patience to examine the spatial distribution of crime. Today, however, crime mapping is experiencing what might be termed an explosion of interest among both scholars and...

Read the free Plain Language Summary for this article on Journal blog. Marine ecosystems and biogeochemical cycles are facing growing pressures from extreme natural events human activities, resulting in a rapid loss of biodiversity changes to functioning food webs (Rees, 2012). This is particularly true benthic webs, which often spatially fragmented inhabited by rare, endangered, or endemic fau...

This paper outlines a critique of Western biomedical theories of what is called mental illness, and presents an alternative way of responding to mental health problems in people from non-Western cultures. The critique, based on what has been called 'postpsychiatry', problematizes some of the key assumptions that underpin the theory and practice of psychiatry, particularly the problem of how it ...